103775-14-0 Usage
Description
Moexiprilat Hydrate is a white crystalline solid that serves as an angiotensin-converting enzyme (ACE) inhibitor and a dimethoxy analog of Quinapril. It is primarily used as an antihypertensive agent, helping to regulate blood pressure and provide cardiovascular support.
Uses
Used in Pharmaceutical Industry:
Moexiprilat Hydrate is used as an ACE inhibitor for the treatment of hypertension. It works by blocking the conversion of angiotensin I to angiotensin II, a potent vasoconstrictor, thereby reducing blood pressure and alleviating the strain on the heart and blood vessels.
Used in Cardiovascular Applications:
Moexiprilat Hydrate is used as an antihypertensive agent to manage high blood pressure and prevent potential cardiovascular complications. Its role in regulating blood pressure makes it a valuable component in the treatment and management of various heart-related conditions.
Used as a Quinapril Analogue:
Moexiprilat Hydrate is used as an analogue of Quinapril, a widely recognized ACE inhibitor. This similarity allows it to be utilized in the development of new pharmaceuticals and treatments for hypertension and other cardiovascular diseases, potentially offering alternative options for patients who may not respond well to Quinapril or require different treatment approaches.
Check Digit Verification of cas no
The CAS Registry Mumber 103775-14-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,3,7,7 and 5 respectively; the second part has 2 digits, 1 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 103775-14:
(8*1)+(7*0)+(6*3)+(5*7)+(4*7)+(3*5)+(2*1)+(1*4)=110
110 % 10 = 0
So 103775-14-0 is a valid CAS Registry Number.
InChI:InChI=1/C25H30N2O7/c1-15(26-19(24(29)30)10-9-16-7-5-4-6-8-16)23(28)27-14-18-13-22(34-3)21(33-2)12-17(18)11-20(27)25(31)32/h4-8,12-13,15,19-20,26H,9-11,14H2,1-3H3,(H,29,30)(H,31,32)/t15-,19-,20-/m0/s1
103775-14-0Relevant articles and documents
The influence of relative humidity and temperature on stability of moexipril hydrochloride in solid phase
Stanisz, Beata
, p. 91 - 96 (2007/10/03)
Kinetic and thermodynamic parameters of the decomposition of moexipril hydrochloride in solid phase in the absence and presence of humidity were calculated. The evaluation of stability of moexipril hydrochloride was followed by the HPLC method. The applied method was validated (evaluation of the following parameters: selectivity, linearity, precision, limit of detection (LOD), limit of quantification (LOQ) and repeatability). The effect of humidity on the stability of MHCl in solid phase at 363 K was described by the equation: In ki = ax + b = (0.0676 ± 0.016) · RH% - (15.53 ± 0.78). Identification of degradation products of MHCl were carried out by the HPLC-MS method.
