103777-98-6

Basic information

• Product Name: N-(N-Benzyloxycarbonyl-L-γ-glutamyl-1-tert.-butylester)-L-asparaginsaeure-di-tert.-butylester
• Synonyms: N-(N-Benzyloxycarbonyl-L-γ-glutamyl-1-tert.-butylester)-L-asparaginsaeure-di-tert.-butylester
• CAS NO: 103777-98-6
• Molecular Weight: 564.676
• Mol File: 103777-98-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-(N-Benzyloxycarbonyl-L-γ-glutamyl-1-tert.-butylester)-L-asparaginsaeure-di-tert.-butylester(CAS DataBase Reference)
• NIST Chemistry Reference: N-(N-Benzyloxycarbonyl-L-γ-glutamyl-1-tert.-butylester)-L-asparaginsaeure-di-tert.-butylester(103777-98-6)
• EPA Substance Registry System: N-(N-Benzyloxycarbonyl-L-γ-glutamyl-1-tert.-butylester)-L-asparaginsaeure-di-tert.-butylester(103777-98-6)

Safety Data

• Hazardous Substances Data: 103777-98-6(Hazardous Substances Data)

Upstream product

• 5891-45-2 (S)-2-(benzyloxycarbonylamino)pentanedioic acid tert-butyl ester 
• 1791-13-5 L-aspartic acid di-tert-butyl ester hydrochloride 
• 13795-73-8 L-aspartic acid di-tert-butyl ester 
• 540-88-5 acetic acid tert-butyl ester 
• 4652-65-7 (S)-2-Benzyloxycarbonylamino-pentanedioic acid 5-methyl ester 

Downstream Products

• 161878-84-8 (S)-2-((S)-4-tert-Butoxycarbonyl-4-{4-[(2-methyl-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-butyrylamino)-succinic acid di-tert-butyl ester 

Relevant articles and documents

The Synthesis and Thymidylate Synthase Inhibitory Activity of L-γ-L-Linked Dipeptide and L-γ-Amide Analogues of 2-Desamino-2-methyl-N10-propargyl-5,8-dideazafolic Acid (ICI 198583)

Sixteen γ-linked dipeptide and four L-Glu-γ-amide analogues of 2-desamino-2-methyl-N10-propargyl-5,8-dideazafolic acid (ICI 198583) have beensynthesized and evaluated as inhibitors of thymidylate synthase (TS).Z-blocked L-Glu-γ-L-linked dipepti