103849-16-7

Basic information

• Product Name: 8-HYDROXY-4-PHENYL-2-CHROMANONE
• Synonyms: 8-HYDROXY-4-PHENYL-2-CHROMANONE
• CAS NO: 103849-16-7
• Molecular Formula: C₁₅H₁₂O₃
• Molecular Weight: 240.25
• Mol File: 103849-16-7.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 373.3°Cat760mmHg
• Flash Point: 158.5°C
• Appearance: /
• Density: 1.288g/cm³
• Vapor Pressure: 4.22E-06mmHg at 25°C
• Refractive Index: 1.631
• CAS DataBase Reference: 8-HYDROXY-4-PHENYL-2-CHROMANONE(CAS DataBase Reference)
• NIST Chemistry Reference: 8-HYDROXY-4-PHENYL-2-CHROMANONE(103849-16-7)
• EPA Substance Registry System: 8-HYDROXY-4-PHENYL-2-CHROMANONE(103849-16-7)

Safety Data

• Hazardous Substances Data: 103849-16-7(Hazardous Substances Data)

Usage

InChI:InChI=1/C15H12O3/c16-13-8-4-7-11-12(9-14(17)18-15(11)13)10-5-2-1-3-6-10/h1-8,12,16H,9H2

Upstream product

• 140-10-3 cis-cinnamic acid 
• 120-80-9 benzene-1,2-diol 
• 103-26-4 methyl cinnamate 
• 140-10-3 (E)-3-phenylacrylic acid 
• 22129-62-0 2-hydroxyphenyl cinnamate 
• 102-92-1 cinnamoyl chloride 

Downstream Products

• 103849-23-6 3-(2,3-Dihydroxy-phenyl)-N-(3,3-diphenyl-propyl)-3-phenyl-propionamide 
• 103849-22-5 3-(2,3-Dihydroxy-phenyl)-N-(1-methyl-3-phenyl-propyl)-3-phenyl-propionamide 
• 103849-24-7 3-(2,3-Dihydroxy-phenyl)-N-(1-methyl-3,3-diphenyl-propyl)-3-phenyl-propionamide 
• 103849-21-4 N-Phenylisopropyl 3-(2,3-dihydroxyphenyl)-3-phenylpropionamide 
• 103849-17-8 3-(2,3-Dihydroxyphenyl)-3-phenylpropionic acid 
• 103849-19-0 3-(2,3-Dihydroxy-phenyl)-3-phenyl-propionyl chloride 
• 103849-29-2 3-(2,3-Dihydroxyphenyl)-3-phenyl-N-(phenylisopropyl)propylamine 
• 103868-34-4 3-[3-(1-Methyl-3-phenyl-propylamino)-1-phenyl-propyl]-benzene-1,2-diol 
• 103849-30-5 3-[3-(3,3-Diphenyl-propylamino)-1-phenyl-propyl]-benzene-1,2-diol 
• 103849-31-6 3-[3-(1-Methyl-3,3-diphenyl-propylamino)-1-phenyl-propyl]-benzene-1,2-diol 

Relevant articles and documents

Selective synthesis of 3,4-dihydrocoumarins and chalcones from substituted aryl cinnamic esters

Coumarins are ubiquitous in plant kingdom and have been used as antitumor, antifungals, anticoagulants, insecticides. Chalcones are also widespread in plant kingdom and have been known to possess diverse biological activities; antibacterial, antifungal, antitumor and anti-inflammatory, etc. As they are considered as important natural products, numerous synthetic approaches have been reported up to the present. We devise a new selective method of preparing dihydrocoumarins and chalcones from aryl cinnamates by the selection of reagents. Dihydrocoumarin derivatives were prepared selectively by using intramolecular cyclization catalyzed by p-toluene sulfonic acid. Also, chalcones were prepared by Fries-rearrangement catalyzed by TiCl4. This method can be used for preparing various coumarin & chalcone compounds.

3,3-DIPHENYLPROPYLAMINES AND PHARMACEUTICAL COMPOSITIONS THEREOF

Novel 3,3-diphenylpropylamines of formula (I) wherein R1 signifies hydrogen or methyl, R2, R3 and R4 independently signify hydrogen, methyl, methoxy, hydroxy, carbamoyl, sulphanoyl or halogen, and X represents a tertiary amino group -NR5, R6, wherein R5 and R6 signify non-aromatic hydrocarbyl groups, which may be the same or different and which together contain at least three carbon atoms, and which may form a ring together with the amine nitrogen, their salts with physiologically acceptable acids and, when the compounds can be in the form of optical isomers, the racemic mixture and the individual enantiomers, their use as drugs, especially as anticholinergic agents, their use for preparing an anticholinergic drug, pharmaceutical compositions containing the novel amines, and methods for preparing the same

DERIVATIVES OF ARYLALKYLAMINES. XXIII. SYNTHESIS OF N-ARYLALKYL-SUBSTITUTED 3--3-PHENYLPROPYLAMINES AND THEIR EFFECT ON THE UPTAKE OF CATECHOLAMINES

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