103876-50-2Relevant articles and documents
Coumarin derivatives and antiallergic agents containing the same
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, (2008/06/13)
A chromene derivative having the general formula (I): STR1 wherein n is 1 to 5 and --O--CH2)n CO2 H group is attached to 5-position, 6-position, 7-position or 8-position, or salts thereof, a process for preparing the same and antiallergic agents containing the same. The compounds of the present invention inhibit the immunological release of chemical mediators such as SRS-A and histamine from mast cell and have an excellent effect in preventing and treating the various allergic diseases such as allergic asthma, allergic dermatitis, allergic nasitis, hives, allergic enteritis and allergic conjunctivitis, especially allergic asthma.