10388-32-6

Basic information

• Product Name: 1-Propanone, 2,3-dibromo-3-(4-bromophenyl)-1-phenyl-
• CAS NO: 10388-32-6
• Molecular Formula: C15H11Br3O
• Molecular Weight: 446.964
• Mol File: 10388-32-6.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 1-Propanone, 2,3-dibromo-3-(4-bromophenyl)-1-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Propanone, 2,3-dibromo-3-(4-bromophenyl)-1-phenyl-(10388-32-6)
• EPA Substance Registry System: 1-Propanone, 2,3-dibromo-3-(4-bromophenyl)-1-phenyl-(10388-32-6)

Safety Data

• Hazardous Substances Data: 10388-32-6(Hazardous Substances Data)

Upstream product

• 98-86-2 acetophenone 
• 1122-91-4 4-bromo-benzaldehyde 
• 22966-09-2 (2E)-3-(4-bromophenyl)-1-phenylprop-2-en-1-one 
• 1774-66-9 3-(4-bromophenyl)-1-phenylprop-2-en-1-one 
• 75-15-0 carbon disulfide 
• 7726-95-6 bromine 
• 2403-27-2 1-(4-bromophenyl)-3-phenyl-2-propen-1-one 

Downstream Products

• 7464-89-3 1,3,6,8-tetramethyl-1H,3H,6H,8H-pyrimido[4,5-g]pteridine-2,4,7,9-tetraone 
• 147622-96-6 5-Amino-6-[(E)-1-(4-bromo-phenyl)-3-oxo-3-phenyl-propenylamino]-1,3-dimethyl-1H-pyrimidine-2,4-dione 
• 22966-09-2 (2E)-3-(4-bromophenyl)-1-phenylprop-2-en-1-one 
• 74990-12-8 5-(4-Bromo-phenyl)-1,3-diphenyl-1,5-dihydro-pyrazol-4-one 
• 74990-04-8 5-(4-Bromo-phenyl)-1-(2,4-dinitro-phenyl)-3-phenyl-1,5-dihydro-pyrazol-4-one 
• 74990-15-1 5-(4-Bromo-phenyl)-1-(2,4-dinitro-phenyl)-3-phenyl-1,5-dihydro-pyrazole-4-thione 
• 1263152-98-2 6-{4-[5-(4-bromophenyl)-3-phenyl-1H-pyrazol-1-ylcarbonyl]-5-methyl-1H-1,2,3-triazol-1-yl}-1,3-dimethylpyrimidine-2,4(1H,3H)-dione 
• 856084-86-1 1-(4-bromo-phenyl)-3,3-dimethoxy-3-phenyl-propan-1-one 
• 84374-77-6 6-(4-Bromo-phenyl)-4-phenyl-1,6-dihydro-pyrimidine-2,5-dithione 
• 84374-83-4 6-(4-Bromo-phenyl)-4-phenyl-1,6-dihydro-pyrimidine-2,5-dione 
• 147623-05-0 8-(4-Bromo-phenyl)-1,3-dimethyl-6-phenyl-1,9-dihydro-pyrimido[4,5-b][1,4]diazepine-2,4-dione 
• 1774-66-9 3-(4-bromophenyl)-1-phenylprop-2-en-1-one 
• 1083-30-3 dihydrochalcone 
• 52168-41-9 3‐(4‐bromophenyl)‐1‐phenylpropan‐1‐one 

Relevant articles and documents

New nicotinic acid-based 3,5-diphenylpyrazoles: design, synthesis and antihyperlipidemic activity with potential NPC1L1 inhibitory activity

Nicotinic acid hydrazide was incorporated into new 4,5-dihydro-5-hydroxy-3,5-diphenylpyrazol-1-yl derivatives. Compounds 6a–h were synthesized, and their antihyperlipidemic activity was evaluated in high cholesterol diet-fed rat model. Compounds 6e, 6f were found to decrease the levels of serum total cholesterol by 14–19% compared to control group. Total triglycerides were also reduced by 24–28% and LDL cholesterol by 16%. As expected from parent niacin, compounds 6e and 6f caused an elevation of HDL cholesterol by 33–41%. Docking study supported the ability of designed compounds to block NPC1L1 active site in a manner similar to that observed with ezetimibe.

Synthesis of vinyl-substituted β-diketones for polymerizable metal complexes

Polymerizable β-diketones for application to metal ion coordination have been prepared and characterized. Bromine-substituted β-diketones were synthesized under Claisen-Schmidt-type condensation conditions. Vinyl groups were substituted for the halide by