103883-03-0

Basic information

• Product Name: EPICATECHIN-(4BETA->8:2BETA-O-7) CATECHIN
• Synonyms: EPICATECHIN-(4BETA->8:2BETA-O-7) CATECHIN;PROCYANIDIN A1
• CAS NO: 103883-03-0
• Molecular Formula: C₃₀H₂₄O₁₂
• Molecular Weight: 576.5
• Product Categories: Catechins & Tannins
• Mol File: 103883-03-0.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 946.0±65.0 °C(Predicted)
• Appearance: /
• Density: 1.766±0.06 g/cm3(Predicted)
• PKA: 8.77±0.70(Predicted)
• CAS DataBase Reference: EPICATECHIN-(4BETA->8:2BETA-O-7) CATECHIN(CAS DataBase Reference)
• NIST Chemistry Reference: EPICATECHIN-(4BETA->8:2BETA-O-7) CATECHIN(103883-03-0)
• EPA Substance Registry System: EPICATECHIN-(4BETA->8:2BETA-O-7) CATECHIN(103883-03-0)

Safety Data

• Hazardous Substances Data: 103883-03-0(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Applications:
EPICATECHIN-(4BETA->8:2BETA-O-7) CATECHIN is used as a therapeutic agent for its antioxidant and anti-inflammatory properties. It can help in the treatment of various diseases and conditions, such as cardiovascular diseases, neurodegenerative disorders, and certain types of cancer, by reducing oxidative stress and inflammation.
Used in Nutraceutical Applications:
EPICATECHIN-(4BETA->8:2BETA-O-7) CATECHIN is used as a dietary supplement to promote overall health and well-being. Its antioxidant properties can help protect the body from the harmful effects of free radicals, while its anti-inflammatory effects can aid in the management of chronic inflammation-related conditions.
Used in Antioxidant Applications:
EPICATECHIN-(4BETA->8:2BETA-O-7) CATECHIN is used as an antioxidant agent to protect cells from oxidative damage caused by free radicals. This can help in the prevention of various diseases, such as cancer, cardiovascular diseases, and neurodegenerative disorders, by reducing the risk of cellular damage and mutations.
Used in Antiviral Applications:
EPICATECHIN-(4BETA->8:2BETA-O-7) CATECHIN is used as an antiviral agent, potentially providing protection against certain viral infections. Its antiviral activity may be attributed to its ability to inhibit viral replication and reduce the adhesion of viral particles to host cells.
Used in Food and Beverage Industry:
EPICATECHIN-(4BETA->8:2BETA-O-7) CATECHIN is used as a natural additive in the food and beverage industry to enhance the taste, color, and shelf life of various products. Its antioxidant properties can help prevent the oxidation of fats and oils, while its anti-inflammatory effects can contribute to the overall health benefits of the products.

Upstream product

• 20315-25-7 procyanidin B₁ 
• 114637-81-9 epicatechin-(4β->6)-epicatechin-(4β->8, 2β->O->7)-catechin 
• 114653-45-1 epicatechin-(4β->8)-epicatechin-(4β->8, 2β->O->7)-catechin 
• 100-53-8 phenylmethanethiol 
• 52-89-1 l-cysteine hydrochloride 

Relevant articles and documents

Syntheses of doubly linked proanthocyanidins using free flavan units as nucleophiles: Insight into the origin of the high regioselectivity of annulation

A synthesis method of doubly linked flavan dimers is reported via the acid-promoted annulation reaction using nascent catechins, (+)-catechin or (-)-epicatechin, as a dianionic partner and an ethylenedioxy-bridged flavan as a dicationic partner. Procyanidins A1 and A2 were synthesized. On the high regioselectivity of the annulation reactions, model experiments and computational studies were carried out.

Structures and antioxidant and intestinal disaccharidase inhibitory activities of A-type proanthocyanidins from peanut skin

Nine compounds including a new A-type proanthocyanidin trimer, epicatechin-(2β→O→7,4β→8)-[catechin-(6→4β)] -epicatechin (8), and a known trimer, epicatechin-(4β→8)-epicatechin- (2β→O→7,4β→8)-catechin (9), being reported for peanut skin for the first time, were isolated and purified. Their structures were determined by spectroscopic methods and by degradation reactions with l-cysteine in acidic conditions. The DPPH radical scavenging activity and the inhibitory activity on maltase and sucrase of the isolated compounds were investigated. All compounds showed strong DPPH scavenging activities (EC50 50 value of 0.088 mg/mL, while compound 9 exhibited the strongest inhibition on sucrase with an IC50 value of 0.091 mg/mL.

Tannins and Related Compounds. LX. Isolation and Characterization of Proanthocyanidins with a Doubly-Linked Unit from Vaccinium vitis-idaea L.

New proanthocyanidin trimers (14 and 15) and tetramers (16 and 17) have been isolated from the whole body of Vaccinium vitis-idaea L. (Ericaceae).The structures of these proanthocyanidins were established by thiolytic degradation and by analyses of the proton and carbon-13 nuclear magnetic resonance spectra.In addition, the presence of (-)-epicatechin (1), (+)-catechin (2), (-)-epigallocatechin (3), (+)-gallocatechin (4), procyanidins B-1 (5), B-3 (6), A-1 (8) and A-2 (9), and cinnamtannins B1 (10), D1 (11), B2 (12) and D2 (13) in this plant was demonstrared.Keywords - Vaccinium vitis-idaea; Ericaceae; doubly-bonded proanthocyanidin; procyanidin; condensed tannin; flavan-3-ol; thiolytic degradation