1039762-40-7Relevant articles and documents
A convenient and practical synthesis of olmesartan medoxomil methyl ether
Pati, Hari Narayan,Lahiri, Saswata,Sabbam, Ramesh Kumar,Vangala, Vijaya Bhaskar,Ramalingam, Boobalan,Hiriyanna, Salmara Ganeshbhat,Bose, Prosenjit
, p. 917 - 920 (2008)
Synthesis of Olmesartan medoxomil methyl ether (2), a potential impurity of Olmesartan medoxomil (1), an angiotensin II receptor blockers is reported for the first time.
An efficient synthetic method and theoretical calculations of olmesartan methyl ether: Study of biological function of AT1 antagonism
Ntountaniotis, Dimitrios,Mavromoustakos, Thomas,Agelis, George,Resvani, Amalia,Tselios, Theodore,Matsoukas, John,Potamitis, Constantinos,Halabalaki, Maria,Skaltsounis, Leandros Alexios,Liapakis, George,Spyridaki, Katerina,Grdadolnik, Simona Golic,Merzel, Franci,Kostidis, Sarantos
, p. 652 - 662 (2015/06/23)
The dissolution of the antihypertensive AT1 antagonist olmesartan in methanol generates in situ a new highly bioactive methyl ether analogue via SN1 mechanism involving an intramolecular proton transfer from carboxyl to hydroxyl group. Theoretical calcula