103994-99-6 Usage
Description
6,7-Difluoro-1-(4-fluorophenyl)-1,4-dihydro-4-oxo-3-quinolinecarboxylic Acid is an arylfluoroquinoline derivative characterized by the presence of two fluorine atoms at the 6,7 positions and a 4-fluorophenyl group. 6,7-Difluoro-1-(4-fluorophenyl)-1,4-dihydro-4-oxo-3-quinolinecarboxylic Acid exhibits potent antibacterial properties and is utilized in the development of new antimicrobial agents.
Uses
Used in Pharmaceutical Industry:
6,7-Difluoro-1-(4-fluorophenyl)-1,4-dihydro-4-oxo-3-quinolinecarboxylic Acid is used as an intermediate in the synthesis of antibacterial agents for the treatment of bacterial infections. Its unique structure and fluorine-containing nature contribute to its enhanced activity against various bacterial strains, making it a valuable component in the development of new antimicrobial drugs.
Used in Research and Development:
In addition to its pharmaceutical applications, 6,7-Difluoro-1-(4-fluorophenyl)-1,4-dihydro-4-oxo-3-quinolinecarboxylic Acid is also utilized in research and development for the study of arylfluoroquinoline chemistry and its potential applications in other fields, such as materials science or agrochemicals. Its unique properties and reactivity make it an interesting subject for further exploration and innovation.
Check Digit Verification of cas no
The CAS Registry Mumber 103994-99-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,3,9,9 and 4 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 103994-99:
(8*1)+(7*0)+(6*3)+(5*9)+(4*9)+(3*4)+(2*9)+(1*9)=146
146 % 10 = 6
So 103994-99-6 is a valid CAS Registry Number.
103994-99-6Relevant articles and documents
Synthesis of norfloxacin analogues catalyzed by Lewis and Br?nsted acids: An alternative pathway
Leyva, Socorro,Hernández, Hiram
, p. 982 - 988 (2010)
An alternative synthetic pathway to prepare norfloxacin analogues is presented. Three Lewis acids (CeCl3·7H2O, AlCl 3·6H2O, ZnCl2) and one Bro?nsted acid (TsOH) were tested as catalysts in the prepara
Baylis-Hillman route to several quinolone antibiotic intermediates
Hong, Wan Pyo,Lee, Kee-Jung
, p. 963 - 968 (2007/10/03)
Treatment of methyl propiolate and 2,4,5-trifluoro-, 2-fluoro-, 2-fluoro-5-methoxy- or 2,3,4,5-tetrafluorobenzaldehydes with a ZrCl 4/Bu4NI combination induces an aldol reaction to furnish β-iodo-α-(hydroxyalkyl)acrylates. These can be used for the preparation of several quinolone intermediates, 1-substituted 4-oxo-1,4-dihydroquinoline-3-carboxylic acids and 9,10-difluoro-3-methyl-2,3- dihydro-7-oxo-7H-pyrido[1,2,3-de][1,4]benzoxazine-6-carboxylic acid through the oxidation, amination and hydrolysis reactions. Georg Thieme Verlag Stuttgart.
Heterocycylic-substituted quinoline-carboxylic acids
-
, (2008/06/13)
1-Substituted-6-fluoro-7-heterocyclic-1,4-dihydroquino-1-(or dihydronaphthyridin)-4-one carboxylic acids have antibacterial properties. The 7-heterocyclic group is a bicyclic group, one of the rings of which is saturated and the other ring of which is unsaturated.