10400-18-7

Basic information

• Product Name: 1-(4-chlorophenyl)-2-methylpropan-1-ol
• CAS NO: 10400-18-7
• Molecular Formula: C₁₀H₁₃ClO
• Molecular Weight: 184.6626
• Mol File: 10400-18-7.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 267.5°C at 760 mmHg
• Flash Point: 115.6°C
• Density: 1.113g/cm³
• Vapor Pressure: 0.00404mmHg at 25°C
• Refractive Index: 1.532
• CAS DataBase Reference: 1-(4-chlorophenyl)-2-methylpropan-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-chlorophenyl)-2-methylpropan-1-ol(10400-18-7)
• EPA Substance Registry System: 1-(4-chlorophenyl)-2-methylpropan-1-ol(10400-18-7)

Safety Data

• Hazardous Substances Data: 10400-18-7(Hazardous Substances Data)

Upstream product

• 1068-56-0 isopropylmagnesium iodide 
• 104-88-1 4-chlorobenzaldehyde 
• 78-84-2 isobutyraldehyde 
• 51833-36-4 4-chlorophenylmagnesium chloride 
• 18713-58-1 1-(4-chlorophenyl)-2-methylpropan-1-one 
• 873-77-8 (4-chlorphenyl)magnesium bromide 
• 1068-55-9 isopropylmagnesium chloride 
• 67-56-1 methanol 
• 3391-10-4 1-(p-chlorophenyl)ethyl alcohol 

Downstream Products

• 19366-15-5 4-chloro-β,β-dimethylstyrene 
• 18713-58-1 1-(4-chlorophenyl)-2-methylpropan-1-one 
• 28094-80-6 7-Chloro-2-(4-chloro-phenyl)-1,1,3,3-tetramethyl-1,2,3,4-tetrahydro-naphthalene 
• 97619-51-7 Maleinsaeure-mono-<2-methyl-1-(4-chlor-phenyl>-propylester> 
• 96875-25-1 2-Methyl-1-<4-chlor-phenyl>-propyl-hydrogensuccinat 
• 97417-43-1 Glutarsaeure-mono-<2-methyl-1-(4-chlor-phenyl)-propylester> 
• 75625-99-9 2-(4'-<2-methyl-1-propenyl>phenyl)propanoic acid 
• 77601-60-6 ethyl 2-<(4-(2-methyl-1-propenyl)phenyl)>propionate 
• 126275-17-0 3-(4-Chloro-phenyl)-4-methyl-pentanoyl chloride 
• 126275-16-9 3-(4-chlorophenyl)-4-methylpentanoic acid 
• 126275-07-8 3-(4-Chloro-phenyl)-4-methyl-pent-3-enoic acid ethyl ester 
• 126275-08-9 (E)-3-(4-Chloro-phenyl)-4-methyl-pent-2-enoic acid ethyl ester 
• 126275-09-0 3-(4-Chloro-phenyl)-4-methyl-pentanoic acid ethyl ester 
• 126275-06-7 3-(4-Chloro-phenyl)-3-hydroxy-4-methyl-pentanoic acid ethyl ester 

Relevant articles and documents

Ruthenium(II)-Catalyzed β-Methylation of Alcohols using Methanol as C1 Source

Selective introduction of methyl branches into the carbon chains of alcohols can be achieved with low loadings of ruthenium precatalyst [RuH(CO)(BH4)(HN(C2H4PPh2)2)] (Ru-MACHO-BH) using methanol both as methylating reagent and as reaction medium. A wide range of structurally divers alcohols was β-methylated with excellent selectivity (>99 %) in fair to high yields (up to 94 %) under standard conditions, and turnover numbers up to 18,000 could be established. The overall reaction rate of the complex catalytic network appears to be governed by interconnection of the individual subcycles through availability of the reactive intermediates. The synthetic procedure opens pathways to important structural motifs following the Green Chemistry principles.

17-Beta hydroxysteroid dehydrogenase type 3 inhibitors for the treatment of androgen dependent diseases

There are disclosed compounds of the formula (I): prodrugs thereof, or pharmaceutically acceptable salts of the compounds or of said prodrugs which are useful as inhibitors of Type 3 17β-Hydroxysteroid Dehydrogenase. Also disclosed are pharmaceutical compositions containing said compounds and their use for the treatment or prevention of androgen dependent diseases.

1,4-diaryl-2,3-difluoro-2-butene insecticidal and acaricidal agents

Pesticidal 1,4-diaryl-2,3-difluoro-2-butene compounds having the structural formula I and compositions and methods comprising those compounds for the control of insect and acarid pests.