104051-69-6 Usage
Explanation
The compound's full name describes its structure and components.
Explanation
The core of the compound is a naphthyridine ring, which is a fused six-membered nitrogen-containing ring and a five-membered ring.
Explanation
The compound contains a carboxylic acid functional group, which is characterized by a carbonyl group (C=O) and a hydroxyl group (-OH) attached to the same carbon.
Explanation
The compound has a fluorine atom (F) substituting one of the hydrogen atoms at the 6th position of the naphthyridine ring.
Explanation
The compound has a difluorophenyl group (a phenyl ring with two fluorine atoms at the 2nd and 4th positions) attached to the 1st position of the naphthyridine ring.
Explanation
The compound has an amino-pyrrolidinyl group (a pyrrolidine ring with an amino group attached to the 3rd position) at the 7th position of the naphthyridine ring.
8. Biological and Pharmacological Applications
Explanation
The compound has potential uses in the fields of biology and pharmacology, possibly as a medication or research tool.
9. Unique Chemical Structure and Functional Groups
Explanation
The specific properties and activities of the compound are determined by its unique chemical structure, which includes the naphthyridine core, carboxylic acid group, fluoro and difluorophenyl substitutions, and the amino-pyrrolidinyl group.
Core Structure
Naphthyridine
Carboxylic Acid Group
-COOH
Fluoro Substitution
6-Fluoro
Difluorophenyl Substitution
1-(2,4-difluorophenyl)
Amino-pyrrolidinyl Group
7-(3-amino-1-pyrrolidinyl)
Check Digit Verification of cas no
The CAS Registry Mumber 104051-69-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,4,0,5 and 1 respectively; the second part has 2 digits, 6 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 104051-69:
(8*1)+(7*0)+(6*4)+(5*0)+(4*5)+(3*1)+(2*6)+(1*9)=76
76 % 10 = 6
So 104051-69-6 is a valid CAS Registry Number.
104051-69-6Relevant articles and documents
Preparation of 7-(3-amino- and 3-amino-methyl-1-pyrrolidinyl)-3-quinolonecarboxylic acids and -naphthyridonecarboxylic acids
-
, (2008/06/13)
Process for the preparation of antibacterial compounds of the formula STR1 comprises condensing an oxo compound of the formula STR2 with an amino compound of the formula STR3 to produce a compound of the formula STR4 reacting the compound of the formula (III) with a compound of the formula STR5 to give a compound of the formula STR6 and then eliminating the amino-protective group STR7
Synthesis and Structure-Activity Relationships of New Arylfluoronaphthyridine Antibacterial Agents
Chu, Daniel T. W.,Fernandes, Prabhavathi B.,Claiborne, Akiyo K.,Gracey, Eugene H.,Pernet, Andre G.
, p. 2364 - 2369 (2007/10/02)
Novel arylfluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid have been prepared and their antibacterial activity evaluated.These derivatives are characterized by having a fluorine atom at 6-position, substituted amino groups at the 7-position, and substituted phenyl groups at the 1-position.The in vitro antibacterial potency is greatest when the 1-substituent is either p-fluorophenyl or o,p-difluorophenyl and the 7-substituent is a 3-amino-1-pyrrolidinyl group. 1-(2,4-Difluorophenyl)-6-fluoro-7-(3-amino-1-pyrrolidinyl)-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid (38) was found to possess excellent in vitro potency and in vivo efficacy.
