10407-20-2

Basic information

• Product Name: Benzaldehyde, (4-methoxyphenyl)hydrazone
• CAS NO: 10407-20-2
• Molecular Formula: C14H14N2O
• Molecular Weight: 226.278
• Mol File: 10407-20-2.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: Benzaldehyde, (4-methoxyphenyl)hydrazone(CAS DataBase Reference)
• NIST Chemistry Reference: Benzaldehyde, (4-methoxyphenyl)hydrazone(10407-20-2)
• EPA Substance Registry System: Benzaldehyde, (4-methoxyphenyl)hydrazone(10407-20-2)

Safety Data

• Hazardous Substances Data: 10407-20-2(Hazardous Substances Data)

Upstream product

• 100-52-7 benzaldehyde 
• 3471-32-7 4-Methoxyphenylhydrazine 
• 100-39-0 benzyl bromide 
• 2725-46-4 1-benzyl-2-benzylidene-1-phenylhydrazine 
• 588-64-7 benzaldehyde phenylhydrazone 
• 104-94-9 4-methoxy-aniline 
• 19501-58-7 4-methoxyphenylhydrazine hydrochloride 

Downstream Products

• 1223079-60-4 4-ethyl(carbethoxy)amino-2-(4-methoxyphenyl)-5-phenyl-2H-1,2,4-triazol-3(4H)-one 
• 60981-60-4 1-(chlorophenylmethylene)-2-(4-methoxyphenyl)hydrazine 
• 123-11-5 4-methoxy-benzaldehyde 
• 100-52-7 benzaldehyde 
• 142108-79-0 2-(4-methoxyphenyl)-4,5-diphenyl-2H-1,2,3-triazole 
• 28772-59-0 1-benzyl-2-benzylidene-1-(4-methoxyphenyl)hydrazine 
• 1200448-90-3 1-(4-methoxyphenyl)-3,6-diphenyl-4-tosyl-1,4,5,6-tetrahydro-1,2,4-triazine 
• 313650-76-9 C₂₂H₂₃N₃O 
• 313650-75-8 C₂₁H₂₁N₃O 
• 88246-22-4 (4-Methoxy-phenyl)-[phenyl-(4,5,6,7-tetrahydro-benzo[1,3]dithiol-2-ylidene)-methyl]-diazene 

Relevant articles and documents

Broad-Spectrum Antifungal Agents: Fluorinated Aryl- and Heteroaryl-Substituted Hydrazones

Fluorinated aryl- and heteroaryl-substituted monohydrazones displayed excellent broad-spectrum activity against various fungal strains, including a panel of clinically relevant Candida auris strains relative to a control antifungal agent, voriconazole (VRC). These monohydrazones displayed less hemolysis of murine red blood cells than that of VRC at the same concentrations, possessed fungicidal activity in a time-kill study, and exhibited no mammalian cell cytotoxicity. In addition, these monohydrazones prevented the formation of biofilms that otherwise block antibiotic effectiveness and did not trigger the development of resistance when exposed to C. auris AR Bank # 0390 over 15 passages.

Sequential [3+2] annulation reaction of prop-2-ynylsulfonium salts and hydrazonyl chlorides: Synthesis of pyrazoles containing functional motifs

A novel sequential [3+2] annulation reaction has been developed using prop-2-ynylsulfonium salts and hydrazonyl chlorides, affording a series of pyrazoles with functional motifs that can be post modified in the preparation of various drugs or drug candidates. Further transformation and gram-scale operations could also be achieved efficiently. This journal is

Radical Addition of Hydrazones by α-Bromo Ketones to Prepare 1,3,5-Trisubstituted Pyrazoles via Visible Light Catalysis

A novel efficient tandem reaction of hydrazones and α-bromo ketones is reported for the preparation of 1,3,5-trisubstituted pyrazoles by visible light catalysis. In this system, the monosubstituted hydrazones show wonderful reaction activity with alkyl radicals, generated from α-bromo ketones. A radical addition followed by intramolecular cyclization affords the important pyrazole skeleton in good to excellent yields. This efficient strategy under mild conditions with wide group tolerance provides a potential approach to the 1,3,5-trisubstituted pyrazoles.