104128-14-5 Usage
Description
(2R)-[(allyloxy)carbonyl]amino(phenyl)acetic acid is a chiral amino acid derivative with a complex structure, featuring a phenyl ring attached to the alpha carbon of the acetic acid moiety and an allyloxy carbonyl group linked to an amino group. (2R)-[(allyloxy)carbonyl]amino(phenyl)acetic acid possesses an R configuration, indicating a specific spatial arrangement of atoms, which may contribute to its potential reactivity and applications in pharmaceutical or industrial fields.
Uses
Used in Pharmaceutical Industry:
(2R)-[(allyloxy)carbonyl]amino(phenyl)acetic acid is used as a potential pharmaceutical candidate due to its unique structure and chirality, which may offer novel therapeutic properties and interactions with biological targets.
Used in Chemical Research:
(2R)-[(allyloxy)carbonyl]amino(phenyl)acetic acid is used as a subject of chemical research to explore its reactivity, potential applications, and safety profiles, furthering the understanding of its properties and possible uses in various industries.
Check Digit Verification of cas no
The CAS Registry Mumber 104128-14-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,4,1,2 and 8 respectively; the second part has 2 digits, 1 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 104128-14:
(8*1)+(7*0)+(6*4)+(5*1)+(4*2)+(3*8)+(2*1)+(1*4)=75
75 % 10 = 5
So 104128-14-5 is a valid CAS Registry Number.
104128-14-5Relevant articles and documents
Dynamic Kinetic Resolution of N-Protected Amino Acid Esters via Phase-Transfer Catalytic Base Hydrolysis
Yamamoto, Eiji,Wakafuji, Kodai,Furutachi, Yuho,Kobayashi, Kaoru,Kamachi, Takashi,Tokunaga, Makoto
, p. 5708 - 5713 (2018/05/30)
Asymmetric base hydrolysis of α-chiral esters with synthetic small-molecule catalysts is described. Quaternary ammonium salts derived from quinine were used as chiral phase-transfer catalysts to promote the base hydrolysis of N-protected amino acid hexafluoroisopropyl esters in a CHCl3/NaOH (aq) via dynamic kinetic resolution, providing the corresponding products in moderate to good yields (up to 99%) with up to 96:4 er. Experimental and computational mechanistic studies using DFT calculation and pseudotransition state (pseudo-TS) conformational search afforded a TS model accounting for the origin of the stereoselectivity. The model suggested π-stacking and H-bonding interactions play essential roles in stabilizing the TS structures.
