1041423-28-2 Usage
Description
3-Chloro-6-fluoro-isoquinoline, a heterocyclic compound with the molecular formula C9H5ClFNO, is characterized by the presence of both chlorine and fluorine atoms within its structure. It is recognized for its potential as a valuable intermediate in the synthesis of complex molecules, making it a promising candidate for various applications across pharmaceutical, agrochemical, and scientific research domains.
Uses
Used in Pharmaceutical Industry:
3-Chloro-6-fluoro-isoquinoline is used as a key intermediate in the development of new drugs, leveraging its unique structural features to enhance the properties of medicinal compounds. Its presence in drug molecules can contribute to improved pharmacokinetics, potency, and selectivity, making it an essential component in the advancement of novel therapeutic agents.
Used in Agrochemical Industry:
In the agrochemical sector, 3-Chloro-6-fluoro-isoquinoline serves as a building block for the creation of innovative crop protection products. Its incorporation into agrochemical formulations can lead to the development of more effective and targeted pest control solutions, thereby enhancing crop yields and food security.
Used in Organic Synthesis:
3-Chloro-6-fluoro-isoquinoline is utilized as a versatile building block in organic synthesis, enabling the production of a wide range of chemical compounds. Its reactivity and structural diversity make it an invaluable tool for chemists in the synthesis of complex organic molecules for various applications, including pharmaceuticals, materials science, and specialty chemicals.
Used in Research and Development:
3-Chloro-6-fluoro-isoquinoline holds significant potential for use in research and development across multiple fields of science and technology. Its unique properties and reactivity make it a valuable subject for exploration in academic and industrial research settings, where it can contribute to the discovery of new chemical reactions, materials, and applications.
Check Digit Verification of cas no
The CAS Registry Mumber 1041423-28-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,4,1,4,2 and 3 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1041423-28:
(9*1)+(8*0)+(7*4)+(6*1)+(5*4)+(4*2)+(3*3)+(2*2)+(1*8)=92
92 % 10 = 2
So 1041423-28-2 is a valid CAS Registry Number.
1041423-28-2Relevant articles and documents
GLYCOLATE OXIDASE INHIBITORS FOR THE TREATMENT OF DISEASE
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Paragraph 001235; 001238; 001255; 001256, (2021/01/22)
Described herein are compounds, methods of making such compounds, pharmaceutical compositions and medicaments containing such compounds, and methods of using such compounds to treat or prevent diseases or disorders associated with a defect in glyoxylate metabolism, for example a disease or disorder associated with the enzyme glycolate oxidase (GO) or alterations in oxalate metabolism. Such diseases or disorders include, for example, disorders of glyoxylate metabolism, including primary hyperoxaluria, that are associated with production of excessive amounts of oxalate.
Discovery of 6-(Fluoro-18F)-3-(1H-pyrrolo[2,3-c]pyridin-1-yl)isoquinolin-5-amine ([18F]-MK-6240): A Positron Emission Tomography (PET) Imaging Agent for Quantification of Neurofibrillary Tangles (NFTs)
Walji, Abbas M.,Hostetler, Eric D.,Selnick, Harold,Zeng, Zhizhen,Miller, Patricia,Bennacef, Idriss,Salinas, Cristian,Connolly, Brett,Gantert, Liza,Holahan, Marie,O'Malley, Stacey,Purcell, Mona,Riffel, Kerry,Li, Jing,Balsells, Jaume,Obrien, Julie A.,Melquist, Stacey,Soriano, Aileen,Zhang, Xiaoping,Ogawa, Aimie,Xu, Serena,Joshi, Elizabeth,Della Rocca, Joseph,Hess, Fred J.,Schachter, Joel,Hesk, David,Schenk, David,Struyk, Arie,Babaoglu, Kerim,Lohith, Talakad G.,Wang, Yaode,Yang, Kun,Fu, Jianmin,Evelhoch, Jeffrey L.,Coleman, Paul J.
, p. 4778 - 4789 (2016/06/13)
Neurofibrillary tangles (NFTs) made up of aggregated tau protein have been identified as the pathologic hallmark of several neurodegenerative diseases including Alzheimer's disease. In vivo detection of NFTs using PET imaging represents a unique opportuni
CYCLOALKYLAMINE SUBSTITUTED ISOQUINOLINE DERIVATIVES
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Page/Page column 110, (2008/12/06)
The invention relates to 6-substituted isoquinoline derivatives of the Formula (I) useful for the treatment and/or prevention of diseases associated with Rho-kinase and/or Rho-kinase mediated phosphorylation of myosin light chain phosphatase, and compositions containing such compounds.
