104211-73-6

Basic information

• Product Name: 1,25-dihydroxy-24,24-dimethyl-22-dehydrovitamin D3
• Synonyms: 1,25-dihydroxy-24,24-dimethyl-22-dehydrovitamin D3
• CAS NO: 104211-73-6
• Molecular Formula: C₂₉H₄₆O₃
• Molecular Weight: 442.67374
• Mol File: 104211-73-6.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 584°Cat760mmHg
• Flash Point: 242.4°C
• Appearance: /
• Density: 1.05g/cm³
• Vapor Pressure: 4.5E-16mmHg at 25°C
• Refractive Index: 1.552
• CAS DataBase Reference: 1,25-dihydroxy-24,24-dimethyl-22-dehydrovitamin D3(CAS DataBase Reference)
• NIST Chemistry Reference: 1,25-dihydroxy-24,24-dimethyl-22-dehydrovitamin D3(104211-73-6)
• EPA Substance Registry System: 1,25-dihydroxy-24,24-dimethyl-22-dehydrovitamin D3(104211-73-6)

Safety Data

• Hazardous Substances Data: 104211-73-6(Hazardous Substances Data)

Usage

Synonyms

1,25-(OH)2-24,24-dimethyl-22-dehydrovitamin D3

Type

Synthetic analog of vitamin D3

Function

Potent regulator of calcium and phosphate metabolism

Therapeutic uses

Treating secondary hyperparathyroidism and osteoporosis

Mechanism of action

Acts as an agonist of the vitamin D receptor

Effects on the body

Stimulates absorption of calcium and phosphate in the intestine, promotes bone mineralization

Additional properties

Immunomodulatory effects, potentially beneficial for autoimmune diseases

Precaution

Should be used under the supervision of a qualified healthcare professional to minimize the risk of adverse effects

InChI:InChI=1/C29H46O3/c1-19(14-16-27(3,4)28(5,6)32)24-12-13-25-21(9-8-15-29(24,25)7)10-11-22-17-23(30)18-26(31)20(22)2/h10-11,14,16,19,23-26,30-32H,2,8-9,12-13,15,17-18H2,1,3-7H3/b16-14+,21-10+,22-11-/t19-,23+,24+,25+,26-,29-/m1/s1

Upstream product

• 104211-71-4 1α,3β,25-trihydroxy-24,24-dimethylcholesta-5,22E-diene 
• 104211-56-5 22ξ-hydroxy-1α,3β-bismethoxymethoxy-26,27-dinorergosta-5,23-diene 
• 104211-70-3 (E)-(R)-6-((1S,3R,8S,9S,10R,13R,14S,17R)-1,3-Bis-methoxymethoxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2,3,3-trimethyl-hept-4-en-2-ol 
• 104211-58-7 (E)-(R)-6-((1S,3R,8S,9S,10R,13R,14S,17R)-1,3-Bis-methoxymethoxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2,3,3-trimethyl-hept-4-en-1-ol 
• 104211-66-7 1α,3β-bismethoxymethoxy-24,24-dimethylcholesta-5,22E,25-triene 
• 104211-67-8 2-[(E)-(R)-4-((1S,3R,8S,9S,10R,13R,14S,17R)-1,3-Bis-methoxymethoxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-1,1-dimethyl-pent-2-enyl]-2-methyl-oxirane 
• 104211-72-5 1α,3β-diacetoxy-25-hydroxy-24,24-dimethylcholesta-5,22E-diene 
• 104211-57-6 1α,3β-bismethoxymethoxy-24,24-dimethylcholesta-5,22E-dien-26-oic acid ethyl ester 
• 104211-74-7 Acetic acid (1S,3R,9S,10R,13R,14R,17R)-3-acetoxy-17-((E)-(R)-5-hydroxy-1,4,4,5-tetramethyl-hex-2-enyl)-10,13-dimethyl-2,3,4,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-1-yl ester 
• 104211-59-8 Methanesulfonic acid (E)-(R)-6-((1S,3R,8S,9S,10R,13R,14S,17R)-1,3-bis-methoxymethoxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2,3,3-trimethyl-hept-4-enyl ester 
• 97453-09-3 1α,3β-bismethoxymethoxypregn-5-ene-20S-carbaldehyde 

Relevant articles and documents

Synthesis and biological activity of 1α-hydroxy-24,24-dimethyl-22E-dehydrovitamin D3 and 1α,25-dihydroxy-24,24-dimethyl-22E-dehydrovitamin D3

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