1042224-77-0 Usage
General Description
The chemical 4-(6-Bromo-pyridin-2-ylamino)-piperidine-1-carboxylic acid tert-butyl ester, with a purity of 98% or higher, has a molecular formula of C15H22BrN3O2 and a molecular weight of 356.27. 4-(6-BroMo-pyridin-2-ylaMino)-piperidine-1-carboxylic acid tert-butyl ester, 98+% C15H22BrN3O2, MW: 356.27 is a tert-butyl ester derivative of 4-(6-bromopyridin-2-ylamino)piperidine-1-carboxylic acid and belongs to the class of piperidines. It is commonly used as a building block in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 1042224-77-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,4,2,2,2 and 4 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1042224-77:
(9*1)+(8*0)+(7*4)+(6*2)+(5*2)+(4*2)+(3*4)+(2*7)+(1*7)=100
100 % 10 = 0
So 1042224-77-0 is a valid CAS Registry Number.
1042224-77-0Relevant articles and documents
IRAK-4 inhibitors. Part II: A structure-based assessment of imidazo[1,2-a]pyridine binding
Buckley, George M.,Ceska, Thomas A.,Fraser, Joanne L.,Gowers, Lewis,Groom, Colin R.,Higueruelo, Alicia Perez,Jenkins, Kerry,Mack, Stephen R.,Morgan, Trevor,Parry, David M.,Pitt, William R.,Rausch, Oliver,Richard, Marianna D.,Sabin, Verity
scheme or table, p. 3291 - 3295 (2009/04/05)
A potent IRAK-4 inhibitor was identified through routine project cross screening. The binding mode was inferred using a combination of in silico docking into an IRAK-4 homology model, surrogate crystal structure analysis and chemical analogue SAR.
