1042385-75-0 Usage
Description
PF-00299804 is a potent, irreversible pan-ErbB inhibitor that targets ErbB1, ErbB2, and ErbB4 receptors with IC50 values of 6 nM, 45.7 nM, and 73.7 nM, respectively.
Uses
Used in Pharmaceutical Industry:
PF-00299804 is used as an anticancer agent for its ability to inhibit the ErbB family of receptors, which play a crucial role in cell growth and proliferation. By targeting these receptors, PF-00299804 can effectively suppress tumor growth and progression, making it a promising candidate for cancer treatment.
Additionally, PF-00299804 can be used in combination with other chemotherapeutic drugs to enhance their efficacy and overcome drug resistance in cancer treatment. Its irreversible binding to the ErbB receptors ensures a sustained inhibition, potentially leading to improved therapeutic outcomes for cancer patients.
Check Digit Verification of cas no
The CAS Registry Mumber 1042385-75-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,4,2,3,8 and 5 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1042385-75:
(9*1)+(8*0)+(7*4)+(6*2)+(5*3)+(4*8)+(3*5)+(2*7)+(1*5)=130
130 % 10 = 0
So 1042385-75-0 is a valid CAS Registry Number.
