10425-07-7

Basic information

• Product Name: Methanone, (4-hydroxy-2-methylphenyl)phenyl-
• CAS NO: 10425-07-7
• Molecular Formula: C14H12O2
• Molecular Weight: 212.248
• Mol File: 10425-07-7.mol
• Article Data: 12

Chemical Properties

• CAS DataBase Reference: Methanone, (4-hydroxy-2-methylphenyl)phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Methanone, (4-hydroxy-2-methylphenyl)phenyl-(10425-07-7)
• EPA Substance Registry System: Methanone, (4-hydroxy-2-methylphenyl)phenyl-(10425-07-7)

Safety Data

• Hazardous Substances Data: 10425-07-7(Hazardous Substances Data)

Upstream product

• 614-32-4 3-methylphenyl benzoate 
• 4072-08-6 (2-hydroxy-3-methylphenyl)(phenyl)methanone 
• 108-39-4 3-methyl-phenol 
• 65-85-0 benzoic acid 
• 98-88-4 benzoyl chloride 
• 1131-80-2 (E)-3-(N,N-dimethylamino)-1-phenyl-2-propen-1-one 
• 98-07-7 Benzotrichlorid 
• 136819-92-6 1-Phenyl-2-octene-1,5,7-trione 
• 3098-18-8 2-hydroxy-4-methylbenzophenone 
• 28178-94-1 4-hydroxy-5-isopropyl-2-methyl-benzophenone 
• 40893-37-6 1-(4-methoxy-2-methylphenyl)phenylmethanone 

Downstream Products

• 614-32-4 3-methylphenyl benzoate 
• 3098-18-8 2-hydroxy-4-methylbenzophenone 
• 108-39-4 3-methyl-phenol 
• 179019-05-7 [2-methyl-4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-phenyl-methanol 
• 179018-61-2 [2-methyl-4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-phenyl-methanone 
• 578-39-2 4-hydroxy-2-methylbenzoic acid 
• 40893-37-6 1-(4-methoxy-2-methylphenyl)phenylmethanone 

Relevant articles and documents

Fries rearrangement at atmospheric pressure using microwave irradiation

A very safe, fast and practical Fries rearrangement with conventional AlCl3 catalyst, carried out in a modified domestic microwave oven at atmospheric pressure is reported.

A comparative study: One pot synthesis of some prochiral ketones using conventional and microwave assisted methods

Polyphosphoric acid (PPA) has been used to synthesize a number of prochiral aryl ketones as well as α,β-unsaturated diaryl ketones by conventional and microwave assisted methods in moderate to good yield. The microwave assisted method is advantageous due to increased yield and high purity of products within incredible short period of time.

LTA4 Hydrolase inhibitors

The present invention provides compounds of the formula Ar1-Q-Ar2-Y-R-Z and pharmaceutically acceptable salts thereof wherein Ar1 and Ar2 are optionally substituted aryl moieties, Z is an optionally substituted nitrogen-containing moiety which may be an acyclic, cyclic or bicyclic amine or an optionally substituted monocyclic or bicyclic nitrogen-containing heteroaromatic moiety; Q is a linking group capable of linking two aryl groups; R is an alkylene moiety; Y is a linking moiety capable of linking an aryl group to an alkylene moiety and wherein Z is bonded to R through a nitrogen atom. The compounds and pharmaceutical compositions of the present invention are useful in the treatment of inflammatory diseases which are mediated by LTB4 production, such as proriasis, ulcerative colitis, IBD and asthma.