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104292-65-1

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104292-65-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 104292-65-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,4,2,9 and 2 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 104292-65:
(8*1)+(7*0)+(6*4)+(5*2)+(4*9)+(3*2)+(2*6)+(1*5)=101
101 % 10 = 1
So 104292-65-1 is a valid CAS Registry Number.

104292-65-1Relevant articles and documents

Iminosugar-based galactoside mimics as inhibitors of galactocerebrosidase: SAR studies and comparison with other lysosomal galactosidases

Biela-Banas, Anna,Ouladi, Farah,Front, Sophie,Gallienne, Estelle,Ikeda-Obatake, Kyoko,Asano, Naoki,Wenger, David A.,Martin, Olivier R.

, p. 2647 - 2652 (2014)

Several families of iminosugar-based galactoside mimics were designed, synthesized, and evaluated as galactocerebrosidase (GALC) inhibitors. They were also tested as inhibitors of lysosomal β- and α-galactosidases in order to find new potent and selective pharmacological chaperones for treatment of the lysosomal storage disorder, Krabbe disease. Whereas 1-C-alkyl imino-l-arabinitols are totally inactive toward the three enzymes, 1-C-alkyl imino-L-galactitols were found to be active only toward α-galactosidase A. Finally, 1-N-iminosugars provided the best results, as 4-epi-isofagomine was found to be a good inhibitor of both lysosomal β-galactosidase and GALC. Further elaboration of this structure is required to achieve selectivity between these two galactosidases.

Free-radical addition-fragmentation reactions in synthesis: A 'second generation' synthesis of (+)- pseudomonic acid C

Keck,Tafesh

, p. 5845 - 5846 (2007/10/02)

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