1043491-86-6

Basic information

• Product Name: (S)-4-(4-bromophenyl)-4,5-dihydrooxazol-2-ylamine
• Synonyms: (S)-4-(4-bromophenyl)-4,5-dihydrooxazol-2-ylamine
• CAS NO: 1043491-86-6
• Molecular Weight: 241.087
• Mol File: 1043491-86-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (S)-4-(4-bromophenyl)-4,5-dihydrooxazol-2-ylamine(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-4-(4-bromophenyl)-4,5-dihydrooxazol-2-ylamine(1043491-86-6)
• EPA Substance Registry System: (S)-4-(4-bromophenyl)-4,5-dihydrooxazol-2-ylamine(1043491-86-6)

Safety Data

• Hazardous Substances Data: 1043491-86-6(Hazardous Substances Data)

Upstream product

• 506-68-3 bromocyane 
• 201403-02-3 (+/-)-2-amino-2-(4-bromophenyl)ethanol 
• 1043488-94-3 (RS)-4-(4-bromophenyl)-4,5-dihydrooxazol-2-ylamine 

Relevant articles and documents

Discovery and Characterization of 2-Aminooxazolines as Highly Potent, Selective, and Orally Active TAAR1 Agonists

2-Aminooxazolines were discovered as a novel structural class of TAAR1 ligands. Starting from a known adrenergic compound 1, structural modifications were made to obtain highly potent and selective TAAR1 ligands such as 12 (RO5166017), 18 (RO5256390), 36 (RO5203648), and 48 (RO5263397). These compounds exhibit drug-like physicochemical properties, have good oral bioavailability, and display in vivo activity in a variety of animal models relevant for psychiatric diseases and addiction.