1043869-10-8

Basic information

• Product Name: N-(tert-butoxycarbonyl)-N-(2-hydroxybenzyl)-2-(4-iodo-2-hydroxy-5-methoxyphenyl)ethylamine
• CAS NO: 1043869-10-8
• Molecular Weight: 499.346
• Mol File: 1043869-10-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-(tert-butoxycarbonyl)-N-(2-hydroxybenzyl)-2-(4-iodo-2-hydroxy-5-methoxyphenyl)ethylamine(CAS DataBase Reference)
• NIST Chemistry Reference: N-(tert-butoxycarbonyl)-N-(2-hydroxybenzyl)-2-(4-iodo-2-hydroxy-5-methoxyphenyl)ethylamine(1043869-10-8)
• EPA Substance Registry System: N-(tert-butoxycarbonyl)-N-(2-hydroxybenzyl)-2-(4-iodo-2-hydroxy-5-methoxyphenyl)ethylamine(1043869-10-8)

Safety Data

• Hazardous Substances Data: 1043869-10-8(Hazardous Substances Data)

Upstream product

• 1043869-08-4 N-(2-hydroxybenzyl)-2-(4-iodo-2-hydroxy-5-methoxyphenyl)ethylamine 
• 24424-99-5 di-tert-butyl dicarbonate 

Downstream Products

• 1043869-36-8 C₂₂H₂₅⁽³⁾H₃INO₅ 
• 1043869-30-2 C₂₂H₂₅⁽³⁾H₃INO₅ 
• 1043869-26-6 N-(tert-butoxycarbonyl)-N-(2-[3H-OCH₃]-methoxybenzyl)-2-(2-[3H-OCH₃]methoxy-5-methoxy-4-iodophenyl)ethylamine 
• 1043869-41-5 N-(2-[3H-OCH₃]-methoxybenzyl)-2-(2-[3H-OCH₃]methoxy-5-methoxy-4-iodophenyl)ethylamine 
• 919797-20-9 2-(((4-iodo-2,5-dimethoxyphenethyl)amino)methyl)phenol 
• 1043868-97-8 2-(4-iodo-2,5-dimethoxyphenyl)-N-[(2-methoxyphenyl)methyl]ethanamine hydrochloride 
• 1043869-18-6 5-iodo-4-methoxy-2-(2-((2-methoxybenzyl)amino)ethyl)phenol 
• 1043869-16-4 C₂₂H₂₈INO₅ 
• 1043869-14-2 C₂₂H₂₈INO₅ 
• 1043869-12-0 N-(tert-butoxycarbonyl)-N-(2-methoxybenzyl)-2-(2,5-dimethoxy-4-iodophenyl)ethylamine 

Relevant articles and documents

High specific activity tritium-labeled N-(2-methoxybenzyl)-2,5-dimethoxy-4-iodophenethylamine (INBMeO): A high-affinity 5-HT2A receptor-selective agonist radioligand

The title compound ([3H]INBMeO) was prepared by an O,O-dimethylation reaction of a t-BOC protected diphenolic precursor using no carrier added tritiated iodomethane in DMF with K2CO3. Removal of the t-BOC protecting group and purification by HPLC afforded an overall yield of 43%, with a radiochemical purity of 99% and specific activity of 164 Ci/mmol. The new radioligand was suitable for labeling human 5-HT2A receptors in two heterologous cell lines and had about 20-fold higher affinity than [3H]ketanserin.