104400-52-4Relevant articles and documents
6-Benzylidenethiazolo[3,2-b]-1,2,4-triazole-5(6H)-ones substituted with ibuprofen: Synthesis, characterization and evaluation of anti-inflammatory activity
Tozkoparan, Birsen,Goekhan, Nesrin,Aktay, Goeknur,Yesilada, Erdem,Ertan, Mevluet
, p. 743 - 750 (2000)
In this study, the synthesis of 3-[1-(4-(2-methylpropyl)phenyl)ethyl]- 1,2,4-triazole-5-thione (2) and its condensed derivatives 6- benzylidenethiazolo[3,2-b]-1,2,4-triazole-5(6H)-ones (2a-u) are described. The structures of the compounds were elucidated by spectral and elemental analysis. In the pharmacological studies, anti-inflammatory activities of these compounds have been screened. Among the compounds examined, the compounds 2 and 2g possessed the most prominent and consistent activity. In gastric ulceration studies the synthesized compounds were generally found to be safe at a 200 mg/kg dose level. (C) 2000 Edition scientifique et medicales Elsevier SAS.
PROGRAMMABLE DENDRITIC DRUGS
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Page/Page column 103, (2019/04/27)
Compounds useful as biologically active compounds are disclosed. The compounds have the following structure (I) or a stereoisomer, tautomer or salt thereof, wherein R1, R2, R3, L, L1, L2, L3/sup
PROGRAMMABLE POLYMERIC DRUGS
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Page/Page column 72, (2019/06/09)
Compounds useful as biologically active compounds are disclosed. The compounds have the following structure (I): (I) or a stereoisomer, tautomer or salt thereof, wherein R1, R2, R3, L, L1, L2, L3, L4, M, m and n are as defined herein. Methods associated w