104411-12-3 Usage
Description
rac Enterodiol-d6, an isotope-labeled compound closely related to Enterolactone (E558950), is a metabolite of sesame lignans such as sesamin and sesamolin. It possesses the ability to inhibit colonic cancer cell growth by inducing cell cycle arrest and apoptosis. Additionally, there is a potential relationship between exposure to rac Enterodiol-d6 and a reduced risk of breast cancer.
Uses
Used in Pharmaceutical Industry:
rac Enterodiol-d6 is used as a research compound for studying its effects on cancer cell growth and apoptosis. It is particularly useful in understanding the mechanisms behind its ability to inhibit colonic cancer cell growth and its potential role in reducing the risk of breast cancer.
Used in Cancer Research:
rac Enterodiol-d6 is used as a tool in cancer research to investigate its potential as a therapeutic agent against colonic and breast cancers. Its ability to induce cell cycle arrest and apoptosis in cancer cells makes it a promising candidate for further study and development.
Used in Drug Development:
rac Enterodiol-d6 is used as a starting point for the development of new drugs targeting cancer. Its unique properties and potential effects on cancer cell growth make it an interesting compound for researchers to explore in the development of novel cancer treatments.
Used in Nutritional Research:
rac Enterodiol-d6 is used in nutritional research to study the relationship between sesame lignans and their metabolites, such as Enterolactone, and their potential health benefits, including the reduction of cancer risk.
Used in Analytical Chemistry:
rac Enterodiol-d6 is used as an internal standard or a labeled compound in analytical chemistry for the quantification and identification of its non-labeled counterpart, Enterolactone, in various biological samples. This helps in understanding the bioavailability, metabolism, and pharmacokinetics of Enterolactone in the human body.
Check Digit Verification of cas no
The CAS Registry Mumber 104411-12-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,4,4,1 and 1 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 104411-12:
(8*1)+(7*0)+(6*4)+(5*4)+(4*1)+(3*1)+(2*1)+(1*2)=63
63 % 10 = 3
So 104411-12-3 is a valid CAS Registry Number.
104411-12-3Relevant articles and documents
Synthesis of the -Labelled Urinary Lignans, Enterolactone and Enterodiol, and the Phytoestrogen Daidzein and its Metabolites Equol and O-Demethylangolensin
Waehaelae, Kristiina,Maekelae, Taru,Baeckstroem, Reijo,Brunow, Goeta,Hase, Tapio
, p. 95 - 98 (2007/10/02)
Methods are described for the synthesis of enterolactone, -trans-2,3-bis(3-hydroxybenzyl)-γ-butyrolactone>, enterodiol, -2,3-bis(3-hydroxybenzyl)butane-1,4-diol>, diadzein, -7-hydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-