1044135-34-3

Basic information

• Product Name: 3-chloro-7-[2-(5-methyl-3,4-dioxocyclohexa-1,5-dienylamino)-2-phenylacetylamino]-8-oxo-5-azabicyclo[4.2.0]oct-3-ene-4-carboxylic acid
• CAS NO: 1044135-34-3
• Molecular Weight: 469.881
• Mol File: 1044135-34-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-chloro-7-[2-(5-methyl-3,4-dioxocyclohexa-1,5-dienylamino)-2-phenylacetylamino]-8-oxo-5-azabicyclo[4.2.0]oct-3-ene-4-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3-chloro-7-[2-(5-methyl-3,4-dioxocyclohexa-1,5-dienylamino)-2-phenylacetylamino]-8-oxo-5-azabicyclo[4.2.0]oct-3-ene-4-carboxylic acid(1044135-34-3)
• EPA Substance Registry System: 3-chloro-7-[2-(5-methyl-3,4-dioxocyclohexa-1,5-dienylamino)-2-phenylacetylamino]-8-oxo-5-azabicyclo[4.2.0]oct-3-ene-4-carboxylic acid(1044135-34-3)

Safety Data

• Hazardous Substances Data: 1044135-34-3(Hazardous Substances Data)

Upstream product

• 76470-66-1 loracarbef 
• 488-17-5 3-methylbenzene-1,2-diol 

Relevant articles and documents

Novel β-lactam antibiotics synthesized by amination of catechols using fungal laccase

Novel cephalosporins, penicillins, and carbacephems were synthesized by amination of catechols with amino-β-lactams like cefadroxil, amoxicillin, ampicillin and the structurally related carbacephem loracarbef using laccase from Trametes sp. All isolated monoaminated products inhibited the growth of several Gram positive bacterial strains in the agar diffusion assay, among them methicillin-resistant Staphylococcus aureus strains and vancomycin-resistant Enterococci. Observed differences in the cytotoxicity and in vivo activity in a Staphy-lococcus-infected, immune suppressed mouse model are discussed.