1044161-89-8Relevant articles and documents
Expedient synthesis and solvent dependent oxidation behavior of a water-soluble IBX derivative
Kommreddy, Amitha,Bowsher, Michael S.,Gunna, Meena R.,Botha, Kirankumar,Vinod, Thottumkara K.
, p. 4378 - 4382 (2008)
IBX derivative 6, synthesized in two steps from 2-aminoterephthalic acid, 8, is soluble in both DMF and water. A variety of alcohols are oxidized using 6 in DMF with ease and selectivity identical to that of parent IBX. However, oxidations carried out in water and other aqueous solvent mixtures using 6 exhibit unique selectivities toward different substrates and provide products different from reactions carried out in DMF. A mechanistic rationale is provided for this solvent dependent behavior of 6.