10447-76-4

Basic information

• Product Name: 2-(CHLOROMETHYL)-5-ETHYLPYRIDINE
• Synonyms: 2-(CHLOROMETHYL)-5-ETHYLPYRIDINE
• CAS NO: 10447-76-4
• Molecular Formula: C₈H₁₀ClN
• Molecular Weight: 155.62
• Mol File: 10447-76-4.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2-(CHLOROMETHYL)-5-ETHYLPYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(CHLOROMETHYL)-5-ETHYLPYRIDINE(10447-76-4)
• EPA Substance Registry System: 2-(CHLOROMETHYL)-5-ETHYLPYRIDINE(10447-76-4)

Safety Data

• Hazardous Substances Data: 10447-76-4(Hazardous Substances Data)

Usage

General Description

2-(Chloromethyl)-5-ethylpyridine is a chemical compound with the molecular formula C8H10ClN. It is a pyridine derivative with a chloromethyl group and an ethyl group attached to the 2 and 5 positions, respectively. 2-(CHLOROMETHYL)-5-ETHYLPYRIDINE is used primarily as an intermediate in the synthesis of pharmaceuticals and agrochemicals. It is also used in the manufacturing of dyes, pigments, and other organic compounds. 2-(Chloromethyl)-5-ethylpyridine is a colorless liquid with a pungent odor and is considered to be hazardous, potentially causing skin and eye irritation, and may have harmful effects if ingested, inhaled, or absorbed through the skin.

Upstream product

• 768-61-6 2-hydroxymethyl-5-ethyl pyridine 

Downstream Products

• 136401-87-1 4-(5-Ethyl-pyridin-2-ylmethoxy)-benzaldehyde 
• 136401-68-8 5-[1-[4-(5-Ethyl-pyridin-2-ylmethoxy)-phenyl]-meth-(Z)-ylidene]-thiazolidine-2,4-dione 

Relevant articles and documents

Mononuclear iron complexes relevant to nonheme iron oxygenases. Synthesis, characterizations and reactivity of Fe-Oxo and Fe-Peroxo intermediates

The new ligand L624E (N,N,N′,N′- tetrakis(5-ethyl-2-pyridylmethyl)ethane-1,2-diamine) was designed as a more robust analog of TPEN (N,N,N′,N′-tetrakis(2-pyridylmethyl)ethane-1, 2-diamine) for which the ability at stabilizing high valent Fe-Oxo and Fe-(hydro)peroxo has been reported. With respect to the latter, the pyridyl β-substituents in L624E do not modify the Fe coordination chemistry. From the FeII precursor, [FeO]2+ and FeIII-(hydro)peroxo intermediates are prepared using the same synthetic methods as those reported for the TPEN analogs. The spectroscopic characteristics of all L624E-Fe complexes are very similar to their TPEN analog. However, [(L624E)FeO]2+ has a greater lifetime than that of [(TPEN)FeO]2+. This can be explained by a restricted bimolecular autodegradation due to the bulkiness provided by the ethyl substituents. Regarding small organic molecule oxidation, [(L624E)FeO]2+ and [(L6 24E)FeOOH]2+ exhibit behaviours that seem to be general for the complexes built with ligands of the TPEN family: [FeO]2+ appears to be efficient to epoxidize olefins, whereas [FeOOH]2+ hydroxylates the aromatic ring of anisole with efficacy. The Royal Society of Chemistry 2009.