104484-79-9

Basic information

• Product Name: methyl 2-(3-phenylpropanoyl)hydrazinecarboxylate
• Synonyms: methyl 2-(3-phenylpropanoyl)hydrazinecarboxylate
• CAS NO: 104484-79-9
• Molecular Formula: C₁₁H₁₄N₂O₃
• Molecular Weight: 222.24046
• Mol File: 104484-79-9.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: methyl 2-(3-phenylpropanoyl)hydrazinecarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 2-(3-phenylpropanoyl)hydrazinecarboxylate(104484-79-9)
• EPA Substance Registry System: methyl 2-(3-phenylpropanoyl)hydrazinecarboxylate(104484-79-9)

Safety Data

• Hazardous Substances Data: 104484-79-9(Hazardous Substances Data)

Upstream product

• 3538-68-9 3-phenylpropanehydrazide 
• 79-22-1 methyl chloroformate 
• 103-25-3 3-phenylpropanoic acid methyl ester 
• 68-12-2 N,N-dimethyl-formamide 
• 645-45-4 hydrocinnamic acid chloride 
• 436155-61-2 methyl 2-[(2E)-3-phenylprop-2-enoyl]hydrazinecarboxylate 

Relevant articles and documents

Intramolecular addition of acyldiazenecarboxylates onto double bonds in the synthesis of heterocycles

Appropriate aryl-substituted unsymmetrical azodicarbonyl compounds, generated from bishydrazides by oxidation, undergo intramolecular cyclisations to furnish a variety of useful heterocycles such as N-substituted oxindoles, carbostyrils, benzazepinones, benzazocinones, benzimidazolones, benzoxazinones and pyrazolones in varying degrees of efficiency. Methods are described to remove the N-acyl groups from the heteroaromatic compounds. Under mildly acidic conditions where equal opportunities are available for an ipso or a normal cyclisation it is the former process that occurs preferentially. Evidence is presented in favour of a C-to-C migration in the ipso product for the formation of a methoxy-substituted carbostyril derivative. One of the spiro substances is shown to participate in dienone-phenol rearrangement to provide the corresponding quinolone-phenol in high yield.