104504-45-2 Usage
Description
L-4-BENZOYLPHENYLALANINE, also known as 4-Benzoyl-L-phenylalanine, is a photoreactive amino acid characterized by its off-white solid appearance. It is easily incorporated into a peptide through solid-phase synthesis, making it a versatile compound in various applications.
Uses
Used in Organic Synthesis:
L-4-BENZOYLPHENYLALANINE is used as an important raw material and intermediate for organic synthesis, particularly due to its photoreactive properties and ease of incorporation into peptides.
Used in Photolabeling Applications:
L-4-BENZOYLPHENYLALANINE is used as a photolabel in various research and diagnostic applications, taking advantage of its ability to be easily incorporated into peptides and its photoreactivity.
Used in Pharmaceutical Industry:
L-4-BENZOYLPHENYLALANINE is used as a key component in the development of new drugs, given its role as an intermediate in organic synthesis and its potential for peptide incorporation.
Used in Research and Development:
L-4-BENZOYLPHENYLALANINE is utilized in research and development for its unique properties, including its photoreactivity and its role in peptide synthesis, which can lead to advancements in various scientific fields.
Check Digit Verification of cas no
The CAS Registry Mumber 104504-45-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,4,5,0 and 4 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 104504-45:
(8*1)+(7*0)+(6*4)+(5*5)+(4*0)+(3*4)+(2*4)+(1*5)=82
82 % 10 = 2
So 104504-45-2 is a valid CAS Registry Number.
InChI:InChI=1/C16H15NO3/c17-14(16(19)20)10-11-6-8-13(9-7-11)15(18)12-4-2-1-3-5-12/h1-9,14H,10,17H2,(H,19,20)/t14-/m0/s1
104504-45-2Relevant articles and documents
Simple and stereocontrolled preparation of benzoylated phenylalanine using friedel - Crafts reaction in trifluoromethanesulfonic acid for photoaffinity labeling
Murai, Yuta,Wang, Lei,Muto, Yasuyuki,Sakihama, Yasuko,Hashidoko, Yasuyuki,Hatanaka, Yasumaru,Hashimoto, Makoto
, p. 2119 - 2126 (2013)
Simple and stereocontrolled preparation of benzoylated phenylalanine derivatives from optically pure phenylalanine using Friedel-Crafts reaction in trifluoromethanesulfonic acid (TfOH) is reported; these derivatives are useful for photoaffinity labeling. Protected or unprotected phenylalanine derivatives were converted to benzoyl derivatives in TfOH at room temperature in a short time without loss of optical purity. The reaction condition was applied to synthesize novel photoreactive phenylalanine derivative, which has two photophores (benzophenone and diazirine). The detail analysis of photo-irradiation for two different photophores contained phenylalanine derivative was also investigated. The Japan Institute of Heterocyclic Chemistry.
Photoreactive benzoylphenylalanines and related peptides
-
, (2008/06/13)
Provided is a benzoylphenylalanine of the formula: STR1 wherein STR2 is in the m or p position; and Pr is a protecting group which is easily cleavable in the presence of a peptide bond by a mild acid or base. This benzoylphenylalanine group is incorporated into a peptide chain which can be attached to a solid substrate having a reactive hydrogen by exposure to low energy ultraviolet light.
