104535-37-7

Basic information

• Product Name: 3,4-DIHYDRO-2H-1,4-BENZOXAZIN-7-OL
• Synonyms: 3,4-DIHYDRO-2H-1,4-BENZOXAZIN-7-OL;3,4-dihydro-2H-benzo[b][1,4]oxazin-7-ol;3,4-Dihydro-2H-benzo[1,4]oxazin-7-ol;2H-1,4-BENZOXAZIN-7-OL, 3,4-DIHYDRO-
• CAS NO: 104535-37-7
• Molecular Formula: C₈H₉NO₂
• Molecular Weight: 151.16
• Mol File: 104535-37-7.mol
• Article Data: 3

Chemical Properties

• Appearance: white powder
• Density: 1.241
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 3,4-DIHYDRO-2H-1,4-BENZOXAZIN-7-OL(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4-DIHYDRO-2H-1,4-BENZOXAZIN-7-OL(104535-37-7)
• EPA Substance Registry System: 3,4-DIHYDRO-2H-1,4-BENZOXAZIN-7-OL(104535-37-7)

Safety Data

• Hazardous Substances Data: 104535-37-7(Hazardous Substances Data)

Usage

General Description

3,4-Dihydro-2H-1,4-benzoxazin-7-ol, also known as DIMBOA, is a naturally occurring chemical compound found in several plants, including maize and wheat. It belongs to the class of benzoxazinoids, which are known for their anti-herbivore and allelopathic activities. DIMBOA has been shown to have insecticidal properties against a variety of pests, making it a potential candidate for use in crop protection. Additionally, it has been found to have allelopathic effects on competing plant species, influencing their growth and development. Due to its bioactive properties, DIMBOA has gained significant attention in the field of agriculture and plant biology.

Upstream product

• 93735-22-9 7-methoxy-3,4-dihydro-2H-benzo-[b][1,4]oxazine 
• 6529-94-8 7-methoxy-2H-1,4-benzoxazin-3-one 
• 67193-97-9 7-hydroxy-2H-benzo[b][1,4]oxazin-3(4H)-one 

Downstream Products

• 258524-52-6 4-benzoyl-7-hydroxy-3,4-dihydro-2H-1,4-benzoxazine 
• 1027218-05-8 (7-oxiranylmethoxy-2,3-dihydro-benzo[1,4]oxazin-4-yl)-phenyl-methanone 
• 1338595-02-0 C₁₈H₁₅NO₃ 

Relevant articles and documents

Novel 2,3-dihydro-1,4-benzoxazines as potent and orally bioavailable inhibitors of tumor-driven angiogenesis

Angiogenesis is vital for solid tumor growth, and its prevention is a proven strategy for the treatment of disease states such as cancer. The vascular endothelial growth factor (VEGF) pathway provides several opportunities by which small molecules can act as inhibitors of endothelial proliferation and migration. Critical to these processes is signaling through VEGFR-2 or the kinase insert domain receptor (KDR) upon stimulation by its ligand VEGF. Herein, we report the discovery of 2,3-dihydro-1,4-benzoxazines as inhibitors of intrinsic KDR activity (IC50 50 a potent (KDR: a promising platform for generating kinase-based antiangiogenic therapeutic agents.

Process for lightening the skin or treating pigmental blemishes using a composition containing benzomorpholine or 3,4-dihydro-2H-1,4-benzoxazine derivatives

A topical process for lightening the skin or treating pigmental blemishes consisting in applying to the part of the skin to be treated a composition containing, as active compounds hydroxybenzomorpholines and derivatives thereof corresponding to the following formula: STR1 in which: R1 represents a hydrogen atom or an alkyl radical having from 1 to 4 carbon atoms, and R2 represents a hydroxyl radical in the 6- or 7-position.