104543-13-7

Basic information

• Product Name: 1-cyclohexyl-2-nitro-2(pyridine-2-thiyl)-propane
• Synonyms: 1-cyclohexyl-2-nitro-2(pyridine-2-thiyl)-propane
• CAS NO: 104543-13-7
• Molecular Weight: 280.391
• Mol File: 104543-13-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-cyclohexyl-2-nitro-2(pyridine-2-thiyl)-propane(CAS DataBase Reference)
• NIST Chemistry Reference: 1-cyclohexyl-2-nitro-2(pyridine-2-thiyl)-propane(104543-13-7)
• EPA Substance Registry System: 1-cyclohexyl-2-nitro-2(pyridine-2-thiyl)-propane(104543-13-7)

Safety Data

• Hazardous Substances Data: 104543-13-7(Hazardous Substances Data)

Upstream product

• 1121-30-8 1-hydroxy-2(1H)-pyridinethione 
• 4749-28-4 2-nitropropene 
• 105398-69-4 Cyclohexanecarboxylic acid 2-thioxo-2H-pyridin-1-yl ester 

Downstream Products

• 103-78-6 4-cyclohexyl-butan-2-one 

Relevant articles and documents

THE INVENTION OF NEW RADICAL CHAIN REACTIONS. PART X. HIGH YIELD RADICAL ADDITION REACTIONS OF αβ-UNSATURATED NITROOLEFINS. AN EXPEDIENT CONSTRUCTION OF THE 25-HYDROXY-VITAMIN D3 SIDE CHAIN FROM BILE ACIDS.

Radicals derived from thiohydroxamic esters 3 readily add to nitroolefins 5 (Z=NO2) to give good yields of α-nitrosulphides.These adducts, where the structure permits, are easily oxidised to carboxylic acids 8 by treatment with alkaline hydrogen peroxide.Reductive cleavage to the corresponding aldehydes or ketones 9 is efficiently carried out by the action of TiCl3.Addition of methyl magnesium iodide to methyl ketone derived from 3α-acetoxy 11-oxo cholanic acid gives steroid 10 possessing the 25-hydroxycholesterol side chain of the vitamin D3 metabolites.Radical additions to 1-phenylthio-2-nitropropene 11 have been briefly studied.