1045704-67-3

Basic information

• Product Name: 2-(4-chloro-2-aminophenyl)-5-methylfuran
• Synonyms: 2-(4-chloro-2-aminophenyl)-5-methylfuran
• CAS NO: 1045704-67-3
• Molecular Weight: 207.659
• Mol File: 1045704-67-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-(4-chloro-2-aminophenyl)-5-methylfuran(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-chloro-2-aminophenyl)-5-methylfuran(1045704-67-3)
• EPA Substance Registry System: 2-(4-chloro-2-aminophenyl)-5-methylfuran(1045704-67-3)

Safety Data

• Hazardous Substances Data: 1045704-67-3(Hazardous Substances Data)

Usage

Chemical class

Furan derivative

Functional groups

Chloro-aminophenyl group, methyl substituent

Usage

Organic synthesis, pharmaceutical research

Purpose

Building block for synthesis of biologically active compounds

Potential applications

Development of new drugs and materials

Unique aspects

Wide range of potential uses, unique chemical structure and properties

Upstream product

• 480439-09-6 5-(4-chloro-2-nitrophenyl)-2-furaldehyde 
• 89-63-4 4-Chloro-2-nitroaniline 
• 98-01-1 furfural 
• 1045704-63-9 2-methyl-5-(4-chloro-2-nitrophenyl)-furan 

Downstream Products

• 1354570-48-1 (3E)-4-[6-chloro-2-(2-nitrophenyl)-1H-indol-3-yl]but-3-en-2-one 
• 1354570-49-2 (3E)-4-[6-chloro-2-(4,5-dimethoxy-2-nitrophenyl)-1H-indol-3-yl]but-3-en-2-one 
• 1353023-87-6 N-[5-chloro-2-(5-methyl-2-furyl)phenyl]-2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)acetamide 
• 1353023-93-4 2-amino-N-[5-chloro-2-(5-methyl-2-furyl)phenyl]acetamide 
• 1045704-72-0 C₁₂H₈ClNOS 
• 900530-20-3 4-methyl-N-[5-chloro-2-(5-methyl-2-furyl)phenyl]benzenesulfonamide 
• 1352548-26-5 1-(6-chloro-1-[(4-methylphenyl)sulfonyl]-1H-indol-2-yl)acetone 
• 1352548-35-6 N-[5-chloro-2-(4-oxopentanoyl)phenyl]-4-methylbenzenesulfonamide 
• 1219474-80-2 (3E)-4-[6-chloro-2-(3,4-dimethoxyphenyl)-1H-indol-3-yl]but-3-en-2-one 
• 1219475-07-6 5-chloro-2-(5-methyl-2-furyl)-N-(4-nitrobenzylidene)aniline 
• 1219474-83-5 (3E)-4-[6-chloro-2-(4-nitrophenyl)-1H-indol-3-yl]but-3-en-2-one 

Relevant articles and documents

Furan ring opening-indole ring closure: Recyclization of 2-(2-aminophenyl)furans into 2-(2-oxoalkyl)indoles

The acid-catalyzed rearrangement of 5-alkyl-2-[2-(sulfonylamino)phenyl] furans into 2-(2-oxoalkyl)indoles is described. When the N-sulfonyl group in the starting compounds was displaced by an N-acyl group, the corresponding indoles were not formed under t

Furan as a 1,3-diketone equivalent: the second type furan recyclization applied to indole synthesis

A new approach for the synthesis of indole derivatives based on protolytic recyclization of 2-alkyl-5-(2-tosylaminoaryl)-furans is described. The furan ring in this unusual transformation formally serves as a 1,3-diketone equivalent.