104597-98-0 Usage
Description
1-Benzyl 2-Methyl (S)-(-)-1,2-Aziridinedicarboxylate is a chiral building block that is widely utilized in the organic stereoselective synthesis of various compounds, such as anticancer agents, antibiotics, and enzyme inhibitors. It is an aziridine carboxylic acid ester derivative known for its synthetic applications in creating chiral aziridines through esterification.
Uses
Used in Pharmaceutical Industry:
1-Benzyl 2-Methyl (S)-(-)-1,2-Aziridinedicarboxylate is used as a key intermediate for the synthesis of chiral aziridines, which are essential components in the development of various pharmaceuticals. These aziridines are crucial in the creation of anticancer agents, antibiotics, and enzyme inhibitors, making this compound a vital player in the advancement of medical treatments.
Used in Chemical Synthesis:
In the field of chemical synthesis, 1-Benzyl 2-Methyl (S)-(-)-1,2-Aziridinedicarboxylate serves as a valuable chiral building block for the production of complex organic molecules. Its unique structure allows for the creation of a wide range of compounds with specific stereochemistry, which is essential for the development of new drugs and materials with targeted applications.
Used in Research and Development:
1-Benzyl 2-Methyl (S)-(-)-1,2-Aziridinedicarboxylate is also used in research and development laboratories to explore new synthetic pathways and develop innovative methods for the production of chiral aziridines. 1-BENZYL 2-METHYL (S)-(-)-1,2-AZIRIDINEDICARBOXYLATE's versatility and reactivity make it an attractive candidate for the synthesis of novel molecules with potential applications in various industries, including pharmaceuticals, agrochemicals, and materials science.
Check Digit Verification of cas no
The CAS Registry Mumber 104597-98-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,4,5,9 and 7 respectively; the second part has 2 digits, 9 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 104597-98:
(8*1)+(7*0)+(6*4)+(5*5)+(4*9)+(3*7)+(2*9)+(1*8)=140
140 % 10 = 0
So 104597-98-0 is a valid CAS Registry Number.
InChI:InChI=1/C12H13NO4/c1-16-11(14)10-7-13(10)12(15)17-8-9-5-3-2-4-6-9/h2-6,10H,7-8H2,1H3/t10-,13?/m0/s1
104597-98-0Relevant articles and documents
Synthesis of homochiral acyclic mono- and bis(α-amino acid)s with oligo(oxyethylene) chains
Belohradsky, Martin,Ridvan, Ludek,Zavada, Jiri
, p. 1319 - 1325 (2003)
Synthesis of homochiral α-amino acids 3a-3e and bis(α-amino acid)s 4a-4e via BF3·Et2O-catalyzed ring-opening of methyl (S)-1-[(benzyloxy)carbonyl]aziridine-2-carboxylate (7) with oligo(ethylene glycol)s and subsequent acid hydrolysis
Selective cleavage of carbamate protecting groups from aziridines with otera's catalyst
Sun, Shan,Tirotta, Ilaria,Zia, Nicholas,Hutton, Craig A.
, p. 411 - 415 (2014/04/03)
Otera's distannoxane catalyst was found to promote the cleavage of carbamate groups from N-protected aziridines. This method enables the chemoselective cleavage of an aziridinyl N-carbobenzyloxy (Cbz) group in the presence of other N-Cbz groups. The selec
Catalytic asymmetric aziridination of α,β-unsaturated aldehydes
Deiana, Luca,Dziedzic, Pawel,Zhao, Gui-Ling,Vesely, Jan,Ibrahem, Ismail,Rios, Ramon,Sun, Junliang,Cordova, Armando
supporting information; experimental part, p. 7904 - 7917 (2011/08/05)
The development, scope, and application of the highly enantioselective organocatalytic aziridination of α,β-unsaturated aldehydes is presented. The aminocatalytic azirdination of α,β-unsaturated aldehydes enables the asymmetric formation of β-formyl aziri