1046136-24-6Relevant articles and documents
Synthesis and biological evaluation of p38α kinase-targeting dialkynylimidazoles
Li, Jing,Kaoud, Tamer S.,Laroche, Christophe,Dalby, Kevin N.,Kerwin, Sean M.
scheme or table, p. 6293 - 6297 (2010/06/11)
Based on the mild, thermal rearrangement of 1,2-dialkynylimidazoles to reactive carbene or diradical intermediates, a series of 1,2-dialkynylimidazoles were designed as potential irreversible p38 MAP kinase α-isoform (p38α) inhibitors. The synthesis of th