1046151-46-5Relevant articles and documents
A concise route for the preparation of nucleobase-simplified cADPR mimics by click chemistry
Li, Lingjun,Lin, Baichuan,Yang, Zhenjun,Zhang, Liangren,Zhang, Lihe
, p. 4491 - 4493 (2008/09/21)
Novel nucleobase-modified cADPR mimics were synthesized by the application of click chemistry. Cu(I)-Huisgen cycloaddition (click reaction) was used to construct 4-amide-1,2,3-triazole nucleobase and connect two building blocks efficiently. A concise protection strategy was used for the synthesis of the corresponding cyclo-pyrophosphate, and the target compounds 6a and 6b were prepared within four steps.
