1046152-34-4

Basic information

• Product Name: C₂₀H₂₀O₂
• Synonyms: C₂₀H₂₀O₂
• CAS NO: 1046152-34-4
• Molecular Weight: 292.378
• Mol File: 1046152-34-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₀H₂₀O₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₀H₂₀O₂(1046152-34-4)
• EPA Substance Registry System: C₂₀H₂₀O₂(1046152-34-4)

Safety Data

• Hazardous Substances Data: 1046152-34-4(Hazardous Substances Data)

Upstream product

• 80151-10-6 4-(3-hydroxy-1-propyn-1-yl)-benzaldehyde 
• 98-54-4 para-tert-butylphenol 

Relevant articles and documents

((((1H-INDOL-3YL) METHYLIDENE)AMINO)OXY)ACETIC ACID DERIVATIVES AND RELATED COMPOUNDS AS PAI-1 INHIBITORS FOR THE TREATMENT OF INPAIREMENT OF THE FIBRINOLYTIC SYSTEM AND OF THROMBOSIS

The present invention relates to indole oxime derivatives of formula (I) wherein: R1 is -OH, -OC1-C8 alkyl, or NH2; R2and R3 are, independently, hydrogen, C1-C8 alkyl, -CH2-C3-C6 cycloalkyl, -CH2-pyridinyl, phenyl, or benzyl; R4 is hydrogen, C1-C8 alkyl, C3-C6 cycloalkyl, -CH2-C3-C6cycloalkyl, phenyl, benzyl, heteroaryl, or -CH2-heteoraryl; X is: formula (II), (III), (IV) or (V).The other substituents are defined in claim 1. The present compounds are PAI-1 inhibitors for the treatment of e.g. impairment of the fibrinolytic system, thrombosis or cardiovascular diseases.