10465-91-5Relevant articles and documents
A convenient synthesis of 3-arylcoumarins from arylacetonitriles
Mhiri,Ladhar,El Gharbi,Le Bigot
, p. 1451 - 1461 (1999)
The condensation of salicylaldehydes with various arylacetonitriles catalyzed by anion-exchange resins such as Amberlite IRA 900, leads to the corresponding 3-arylcoumarins in good yields and selectivity.
Dual Role of Oxoaldehydes: Divergent Synthesis of 3-Aryl- and 3-Aroylcoumarins
Moazzam, Ali,Khodadadi, Meysam,Jafarpour, Farnaz,Ghandi, Mehdi
, p. 3630 - 3637 (2022/02/16)
A facile and efficient synthetic approach to various valuable 3-aryl- and 3-aroylcoumarins by the direct arylation and aroylation of coumarins with glyoxals in a metal-free manner is presented. The aryl glyoxal is for the first time recognized to serve as an aryl surrogate in addition to its role as an aroyl transfer reagent via a simple switch in reaction conditions. The approach accommodates a broad substrate scope and high yields of the two types of cross-coupling reactions starting from identical starting materials.
Combatting AMR: A molecular approach to the discovery of potent and non-toxic rhenium complexes active against C. albicans-MRSA co-infection
Crochet, Aurélien,Pavic, Aleksandar,Radakovic, Natasa,Roch, Paul,Sovari, Sara Nasiri,Zobi, Fabio
supporting information, (2021/09/28)
Antimicrobial resistance (AMR) is a major emerging threat to public health, causing serious issues in the successful prevention and treatment of persistent diseases. While the problem escalates, lack of financial incentive has lead major pharmaceutical co
Pd-catalysed carbonylative annulation of salicylaldehydes with benzyl chlorides using N-formylsaccharin as a CO surrogate
Yadav, Vinod K.,Srivastava, Vishnu P.,Yadav, Lal Dhar S.
supporting information, p. 16281 - 16286 (2018/10/04)
A convenient and highly efficient Pd-catalysed carbonylative annulation of salicylaldehydes with benzyl chlorides to afford the corresponding 3-arylcoumarins in good to excellent yields has been developed. Importantly, the protocol utilizes a commercially available, low cost, solid and easy to handle N-formylsaccharin as an alternative to the highly toxic CO gas.