104655-85-8

Basic information

• Product Name: Thymidine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-, 3'-[bis(1-methylethyl)phosphonamidate]
• CAS NO: 104655-85-8
• Molecular Formula: C37H46N3O8P
• Molecular Weight: 691.761
• Mol File: 104655-85-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Thymidine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-, 3'-[bis(1-methylethyl)phosphonamidate](CAS DataBase Reference)
• NIST Chemistry Reference: Thymidine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-, 3'-[bis(1-methylethyl)phosphonamidate](104655-85-8)
• EPA Substance Registry System: Thymidine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-, 3'-[bis(1-methylethyl)phosphonamidate](104655-85-8)

Safety Data

• Hazardous Substances Data: 104655-85-8(Hazardous Substances Data)

Upstream product

• 108-18-9 diisopropylamine 
• 180475-92-7 2,4,6-Trichlorophenyl 5'-O-dimethoxytritylthymidin-3'-yl phosphonate 
• 56183-63-2 bis(diisopropylamino)chlorophosphine 
• 40615-39-2 5'-O-(4-4'-dimethoxytrityl)thymidine 

Downstream Products

• 31281-82-0 5'-O-(p,p'-Dimethoxytrityl)thymidine 3'-monophosphate 

Relevant articles and documents

Aryl H-phosphonates. 6. Synthetic studies on the preparation of nucleoside N-alkyl-H-phosphonamidates

Various approaches to the synthesis of nucleoside H-phosphonamidates have been investigated. Direct couplings of nucleoside H-phosphonates with amines have been hampered by extensive reactions of the condensing agents with amines. Preactivation of nucleos