104683-06-9

Basic information

• Product Name: 1-(6-chloro-2-phenyl-1H-indol-1-yl)ethan-1-one
• Synonyms: 1-(6-chloro-2-phenyl-1H-indol-1-yl)ethan-1-one
• CAS NO: 104683-06-9
• Molecular Weight: 269.73
• Mol File: 104683-06-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-(6-chloro-2-phenyl-1H-indol-1-yl)ethan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(6-chloro-2-phenyl-1H-indol-1-yl)ethan-1-one(104683-06-9)
• EPA Substance Registry System: 1-(6-chloro-2-phenyl-1H-indol-1-yl)ethan-1-one(104683-06-9)

Safety Data

• Hazardous Substances Data: 104683-06-9(Hazardous Substances Data)

Upstream product

• 104683-02-5 N-(5-chloro-2-(phenylethynyl)phenyl)acetamide 

Downstream Products

• 57039-63-1 6-chloro-2-phenylindole 

Relevant articles and documents

PtCl4-catalyzed cyclization of N-acetyl-2-alkynylanilines: A mild and efficient synthesis of N-acetyl-2-substituted indoles

An efficient synthesis of N-acetyl-2-substituted indole derivatives via direct intramolecular hydroamination of N-acetyl-2-alkynylaniline derivatives was developed. The reaction could be applied to a wide range of substrates employing only 1–2 mol% of PtCl4 as the catalyst to furnish the desired indole products in moderate to excellent yields. The current protocol is efficient, reliable and scalable, and could serve as an important tool for convenient and rapid access to this important class of N-heterocyclic skeleton from readily available substrates.