10469-34-8

Basic information

• Product Name: N--N-methyl-anilin
• Synonyms: N--N-methyl-anilin
• CAS NO: 10469-34-8
• Molecular Weight: 201.628
• Mol File: 10469-34-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N--N-methyl-anilin(CAS DataBase Reference)
• NIST Chemistry Reference: N--N-methyl-anilin(10469-34-8)
• EPA Substance Registry System: N--N-methyl-anilin(10469-34-8)

Safety Data

• Hazardous Substances Data: 10469-34-8(Hazardous Substances Data)

Upstream product

• 433-52-3 methyl chlorofluoroacetate 
• 35954-01-9 lithium N-methylanilide 
• 100-61-8 N-methylaniline 
• 359-32-0 chlorofluoroacetyl chloride 
• 2588-70-7 N-Methyl-N-<2-chlor-1.2-difluor-vinyl>-anilin 

Downstream Products

• 155094-49-8 N-(2-Chloro-2-fluoroethyl)-N-methylaniline 

Relevant articles and documents

Electrolytic Reactions of Fluoroorganic Compounds. 14. Regioselective Anodic Methoxylation of N-(Fluoroethyl)amines. Preparation of Highly Useful Fluoroalkylated Building Blocks

Anodic methoxylation of various types of N-(fluoroethyl)amines, ArRNCH2Rf (Rf = CF3, CHF2, CH2F, etc.) has been systematically studied and it was found that a methoxy group was exclusively or preferentially introduced into the position α to the fluoromethyl (Rf) group, depending on the Rf and R groups.The effect of the Rf group on the promotion of the anodic α-methoxylation decreased in the order CF3, CHF2, and CH2F.This remarkable promotion effect and unique regioselectivity can be explained mainly in terms of the α-CH kinetic acidities of the cation radicals formed by one-electron oxidation of the amines.The α-methoxylated products are highly useful precursors for the construction of carbon-carbon bonds α to the trifluoromethyl and difluoromethyl groups, which is difficult by other methods.