10472-24-9Relevant articles and documents
Oxidative Cyclization of Dicarboxylate Dienolates as a New Cyclization Method
Chung, Sung Kee,Dunn, Larson B.
, p. 1125 - 1127 (1983)
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Synthesis of dimethyl adipate from cyclopentanone and dimethyl carbonate over solid base catalysts
Wu, Dudu,Chen, Zhi,Jia, Zhenbin,Shuai, Li
, p. 380 - 385 (2012)
A facile route for the synthesis of dimethyl adipate (DAP) from cyclopentanone and dimethyl carbonate (DMC) in the presence of solid base catalysts has been developed. It was found that the intermediate carbomethoxycyclopentanone (CMCP) was produced from cyclopentanone with DMC in the first step, and then CMCP was further converted to DAP by reacting with a methoxide group. The role of the basic catalysts can be mainly ascribed to the activation of cyclopentanone via the abstraction of a proton in the α-position by base sites, and solid bases with moderate strength, such as MgO, favor the formation of DAP.
The profound effect of the ring size in the electrocyclic opening of cyclobutene-fused bicyclic systems
Ralph, Michael J.,Harrowven, David C.,Gaulier, Steven,Ng, Sean,Booker-Milburn, Kevin I.
, p. 1527 - 1531 (2015)
Fused cyclobutenes, prepared by the photocycloaddition of propargyl alcohols to cyclic anhydride chromophores, undergo facile thermochemical ring opening to fused γ-lactones. The size of the fused ring profoundly influences the temperature that is required to facilitate the ring opening (from 50°C to 180°C) and the nature of the product that is formed. Our studies provide new insights into the mechanistic course of these reactions and have been extended to facilitate the preparation of lactams fused to medium-sized rings.
Catalytic TMSCl promoted powerful aldol addition and Claisen condensation mediated by TiCl4/Bu3N agent: Comparison and evaluation with the Mukaiyama aldol addition
Yoshida, Yoshihiro,Matsumoto, Noriaki,Hamasaki, Ryota,Tanabe, Yoo
, p. 4227 - 4230 (1999)
TMSCl catalyst (0.05 equiv) significantly promoted the TiCl4/Bu3N-mediated direct cross aldol additions of sterically crowded ketones and α-hetero substituted ketones, and also the direct Claisen condensation between methyl esters.
INHIBITORS OF LYSINE BIOSYNTHESIS VIA THE DIAMINOPIMELATE PATHWAY
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Paragraph 0271, (2020/01/24)
The present invention relates to compounds that have the ability to inhibit lysine biosynthesis via the diaminopimelate pathway in certain organisms. As a result of this activity these compounds can be used in applications where inhibition of lysine biosynthesis is useful. Applications of this type include the use of the compound as herbicides and/or anti-bacterial agents.
Synthesis method of 2-methyl oxycyclopentane carboxylate
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Paragraph 0025; 0040-0063, (2018/09/13)
The invention discloses a synthesis method of 2-methyl oxycyclopentane carboxylate. Dimethyl adipate used as a main raw material reacts with alkaline for intramolecular cyclization, and then methanolis eliminated for one minute to obtain a target compound. The whole synthesis process simplifies the operation, and produces a relatively small amount of wastewater. According to the synthesis method,the condensation reaction and the elimination reaction are completed by only one type of alkali, so that the number of material varieties is reduced, and the operation efficiency is improved. No prohibited chemicals such as samarium diiodide and mercury are used in the synthesis method; no strong alkali such as butyl lithium is used either; ultralow temperature is not required, so that the production cost is reduced; and in a word, the synthesis method disclosed by the invention has the following characteristics of mild reaction conditions, simple technological operation, environmental friendliness, low cost and high yield.