1047650-51-0 Usage
Description
N-[menthyloxycarbonyl]-L-leucine, also known as MPAA, is a menthol-derived mono-protected L-amino acid ligand that has been developed for use in β-arylation C-H functionalization. It is a chemical compound derived from menthol and L-leucine, an essential amino acid, and is characterized by its unique structure and properties.
Uses
Used in Chemical Synthesis:
N-[menthyloxycarbonyl]-L-leucine is used as a ligand in the β-arylation C-H functionalization process for the synthesis of various organic compounds. Its unique structure allows for selective and efficient functionalization of aromatic compounds, which is crucial in the development of new pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Pharmaceutical Industry:
N-[menthyloxycarbonyl]-L-leucine is used as a key intermediate in the synthesis of complex organic molecules, particularly in the pharmaceutical industry. Its ability to facilitate β-arylation C-H functionalization makes it a valuable tool for the development of novel drug candidates with improved potency, selectivity, and pharmacokinetic properties.
Used in Research and Development:
N-[menthyloxycarbonyl]-L-leucine is also used as a research tool in academic and industrial laboratories, where it can be employed to study the mechanisms of C-H functionalization and to develop new synthetic methodologies. This can lead to the discovery of innovative approaches for the synthesis of complex organic molecules and the advancement of chemical science.
Check Digit Verification of cas no
The CAS Registry Mumber 1047650-51-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,4,7,6,5 and 0 respectively; the second part has 2 digits, 5 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1047650-51:
(9*1)+(8*0)+(7*4)+(6*7)+(5*6)+(4*5)+(3*0)+(2*5)+(1*1)=140
140 % 10 = 0
So 1047650-51-0 is a valid CAS Registry Number.
1047650-51-0Relevant articles and documents
PdII-catalyzed enantioselective activation of C(sp 2)-H and C(sp3)-H bonds using monoprotected amino acids as chiral ligands
Shi, Bing-Feng,Maugel, Nathan,Zhang, Yang-Hui,Yu, Jin-Quan
supporting information; experimental part, p. 4882 - 4886 (2009/02/08)
(Chemical Equation Presented) The relay of chiral information from the α-carbon atom of the amino acid ligand is believed to be crucial for chiral induction in the PdII-catalyzed enantioselective C-H activation/C-C coupling reaction of diphenyl
