1048-17-5 Usage
Chemical structure
TASP is a bicyclic heterocycle with a spiro-ring structure containing a spiro nitrogen and oxygen atom.
Synonyms
TASP is also known as 1,3,8-Triazaspiro[4.5]decan-4-one,1-phenyl-8-(2-phenylethyl)-.
Synthesis
TASP is synthesized through a multistep reaction process.
Pharmaceuticals
Due to its unique spiro-ring structure, TASP can be a valuable building block for drug discovery and development.
Agrochemicals
TASP's structure also makes it potentially useful in the development of agrochemicals.
Ligand in metal-catalyzed reactions
TASP's properties may allow it to act as a ligand in metal-catalyzed reactions, which are important in various chemical processes.
Check Digit Verification of cas no
The CAS Registry Mumber 1048-17-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,0,4 and 8 respectively; the second part has 2 digits, 1 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1048-17:
(6*1)+(5*0)+(4*4)+(3*8)+(2*1)+(1*7)=55
55 % 10 = 5
So 1048-17-5 is a valid CAS Registry Number.
1048-17-5Relevant articles and documents
Discovery of N-(2-aryl-cyclohexyl) substituted spiropiperidines as a novel class of GlyT1 inhibitors
Pinard, Emmanuel,Ceccarelli, Simona M.,Stalder, Henri,Alberati, Daniela
, p. 349 - 353 (2007/10/03)
Screening of the Roche compound library led to the identification of cis-N-(2-phenyl-cyclohexyl)-spiropiperidine 1 as structurally novel GlyT1 inhibitor. The SAR, which was developed in this series, resulted in the discovery of highly potent compounds displaying excellent selectivity against the GlyT2 isoform.
