104829-88-1Relevant articles and documents
SYNTHESIS, MOLECULAR STRUCTURE, AND ABSOLUTE CONFIGURATION OF 1-α-PHENYLETHYL-3-(2-CYANOETHYL)-4-PIPERIDONE
Grishina, G. V.,Abdulganeeva, S. A.,Potapov, V. M.,Ivanova, I. A.,Espenbetov, A. A.,et al.
, p. 1362 - 1368 (2007/10/02)
The Michael addition of acrylonitrile to the pyrrolidine enamine of 1-(S-α-phenylethyl)-4-piperidone proceeds with the formation of 1:1 mixture of 1-(S-α-phenylethyl)-3-(2-cyanoethyl)-4-piperidone diastereomers.A diastereomer isolated in pure form was sho