1048610-06-5

Basic information

• Product Name: 1-benzyl-6'-bromo-3',4'-dihydro-spiro[piperidine-4,2'(1'H)-quinazoline]-4'-one
• Synonyms: 1-benzyl-6'-bromo-3',4'-dihydro-spiro[piperidine-4,2'(1'H)-quinazoline]-4'-one
• CAS NO: 1048610-06-5
• Molecular Weight: 386.291
• Mol File: 1048610-06-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-benzyl-6'-bromo-3',4'-dihydro-spiro[piperidine-4,2'(1'H)-quinazoline]-4'-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-benzyl-6'-bromo-3',4'-dihydro-spiro[piperidine-4,2'(1'H)-quinazoline]-4'-one(1048610-06-5)
• EPA Substance Registry System: 1-benzyl-6'-bromo-3',4'-dihydro-spiro[piperidine-4,2'(1'H)-quinazoline]-4'-one(1048610-06-5)

Safety Data

• Hazardous Substances Data: 1048610-06-5(Hazardous Substances Data)

Upstream product

• 3612-20-2 1-phenylmethyl-4-piperidone 
• 16313-66-9 5-bromoanthranilamide 

Relevant articles and documents

Spirocyclic derivatives as histone deacetylase inhibitors

This invention is related to new histone deacetylase inhibitors according to the general formula (I) wherein: the dotted line is an optional additional bond; n is zero or an integer from 1 to 4; R1 is hydrogen; C1-C6 alkyl, optionally substituted by aryl or by heteroaryl; (CO)R3; (SO2)R4; aryl; or heteroaryl; R2 is C1-C6 alkyl, optionally substituted by aryl or by heteroaryl; aryl; heteroaryl; or (CO)R5; X is CH2, oxygen or NR6; Y is a bond, CHR7 or NR8; Z is oxygen, CR9R10 or C=R11; and R3, R4, R5, R6, R3 R8, R9, R10 and R11 are as further defined in the specification; and pharmaceutical acceptable salts thereof.