1048681-66-8Relevant articles and documents
Finding the proton in a key intermediate of anti-markovnikov alkyne hydration by a bifunctional catalyst
Grotjahn, Douglas B.,Kragulj, Elijah J.,Zeinalipour-Yazdi, Constantinos D.,Miranda-Soto, Valentin,Lev, Daniel A.,Cooksy, Andrew L.
supporting information; experimental part, p. 10860 - 10861 (2009/02/05)
The secondary structure of a bifunctional catalyst positions a crucial reactive proton in the final intermediate of anti-Markovnikov alkyne hydration to give an aldehyde. NMR coupling and isotopic labeling studies elucidate the location of this proton and its involvement in hydrogen bonding. Copyright