1048958-18-4

Basic information

• Product Name: 2-(4-methoxyphenyl)-1-(naphthalen-1-yl)-1,2,3,4-tetrahydroisoquinoline
• Synonyms: 2-(4-methoxyphenyl)-1-(naphthalen-1-yl)-1,2,3,4-tetrahydroisoquinoline
• CAS NO: 1048958-18-4
• Molecular Weight: 365.475
• Mol File: 1048958-18-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-(4-methoxyphenyl)-1-(naphthalen-1-yl)-1,2,3,4-tetrahydroisoquinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-methoxyphenyl)-1-(naphthalen-1-yl)-1,2,3,4-tetrahydroisoquinoline(1048958-18-4)
• EPA Substance Registry System: 2-(4-methoxyphenyl)-1-(naphthalen-1-yl)-1,2,3,4-tetrahydroisoquinoline(1048958-18-4)

Safety Data

• Hazardous Substances Data: 1048958-18-4(Hazardous Substances Data)

Upstream product

• 78317-83-6 2-(4-methoxyphenyl)-1,2,3,4-tetrahydroisoquinoline 
• 13922-41-3 1-Naphthylboronic acid 
• 703-55-9 1-naphthylmagnesiumbromide 

Relevant articles and documents

Direct sp3 C-H bond arylation, alkylation, and amidation of tetrahydroisoquinolines mediated by hypervalent iodine(iii) under mild conditions

We have developed a method for the sp3 C-H bond functionalization of tetrahydroisoquinolines (THIQs) mediated by [bis(trifluoroacetoxy)iodo]benzene (PIFA). The treatment of the THIQs with various nucleophiles in the presence of PIFA in a green solvent alternative gave the coupled products, with a C-C, C-N, or quaternary carbon center in high yields. This journal is

Copper-catalyzed oxidative sp3 C-H bond arylation with aryl boronic acids

(Chemical Equation Presented) An efficient method was developed for arylation of sp3 C-H bonds using copper bromide as catalyst in absence of directing group with arylboronic acids. The oxidative arylation provides easy access to biologically a