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1049103-12-9

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1049103-12-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1049103-12-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,4,9,1,0 and 3 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1049103-12:
(9*1)+(8*0)+(7*4)+(6*9)+(5*1)+(4*0)+(3*3)+(2*1)+(1*2)=109
109 % 10 = 9
So 1049103-12-9 is a valid CAS Registry Number.

1049103-12-9Relevant articles and documents

Thioether acetamides as P3 binding elements for tetrahydropyrido-pyrazole cathepsin S inhibitors

Wiener, Danielle K.,Lee-Dutra, Alice,Bembenek, Scott,Nguyen, Steven,Thurmond, Robin L.,Sun, Siquan,Karlsson, Lars,Grice, Cheryl A.,Jones, Todd K.,Edwards, James P.

scheme or table, p. 2379 - 2382 (2010/07/14)

A series of tetrahydropyrido-pyrazole cathepsin S (CatS) inhibitors with thioether acetamide functional groups were prepared with the goal of improving upon the cellular activity of amidoethylthioethers. This Letter describes altered amide connectivity, in conjunction with changes to other binding elements, resulting in improved potency, as well as increased knowledge of the relationship between this chemotype and human CatS activity.

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