104971-12-2Relevant articles and documents
A fine-tuned molybdenum hexacarbonyl/phenol initiator for alkyne metathesis
Sashuk, Volodymyr,Ignatowska, Jolanta,Grela, Karol
, p. 7748 - 7751 (2004)
A new, highly potent activator for molybdenum hexacarbonyl and 2-fluorophenol is described. An "instant" catalyst formed in situ from molybdenum hexacarbonyl and 2-fluorophenol shows high activity for cross- and ring-closing alkyne metathesis reaction. The use of 2-fluorophenol can be combined with other activation methods to allow alkyne metathesis at relatively low temperature (80 °C).
Flash Vacuum Pyrolysis of Stabilised Phosphorous Ylides. Part 3. Preparation of o-Methoxyphenyl- and o-Methylsulfanylphenyl-alkynes and their Cyclisation to Benzofuranes and Benzothiophenes
Aitken, R. Alan,Burns, Graham
, p. 2455 - 2460 (2007/10/02)
Fourteen new β-oxo phosphorus ylides 1 - 14 bearing o-methoxybenzoyl or o-(methylsulfanyl)benzoyl groups have been prepared and their pyrolytic behaviour studied.While flash vacuum pyrolysis (FVP) at 700 deg C brings about extrusion of Ph3PO to give the expected alkynes 16, this is accompained at 850 deg C by loss of Me* and cyclisation of the resulting radicals to afford 2-substituted benzofurans or benzothiophenes 17 - 24.Where the substituent R1 on the ylidic carbon of the starting material is phenyl, this is incorporated unchanged into the heterocyclic products.Where R1 is Et or Pri the vinyl products are formed by intramolecular abstraction of a β-hydrogen atom following cyclisation.For R1 = Me, Pr, Bu, and C5H11 the cyclisation is followed by hydrogen atom abstraction from the alkyl group leading to its fragmentation and giving products with 2-methyl, ethyl and vinyl substituents.In these cases the products can be accounted for by a radical chain reaction involving the unusual homolytic substitution of a carbon radical at a saturated carbon atom.
A Versatile Two-Stage Synthesis of 2-Substituted Benzofurans from (2-Methoxyphenyl)ethynes
Buckle, Derek, R.,Rockell, Caroline J. M.
, p. 2443 - 2446 (2007/10/02)
(2-Methoxyphenyl)ethynes react with aryl or alkyl halides to give disubstituted alkynes which are converted into the corresponding 2-substituted benzofurans on treatment with lithium iodide in 2,4,6-trimethylpyridine.