104987-36-2

Basic information

• Product Name: oenothein B
• Synonyms: oenothein B;Aids085163;Aids-085163;D-Glucose, cyclic 4,6-(4-(6-carboxy-2,3,4-trihydroxyphenoxy)-4',5,5',6,6'-pentahydroxy(1,1'-biphenyl)-2,2'-dicarboxylate) 2-(2-((6,6'-dicarboxy-2,2',3,3',4'-pentahydroxy(1,1'-biphenyl)-4-yl)oxy)-3,4,5-trihydroxybenzoate) 3-(3,4,5-trihydroxybenzoate), cyclic ester with D-glucose 3-(3,4,5-trihydroxybenzoate), (2(S),4(S))-
• CAS NO: 104987-36-2
• Molecular Formula: C68H48O44
• Molecular Weight: 1569.08
• Mol File: 104987-36-2.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• Density: 2.20±0.1 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 5.67±0.70(Predicted)
• CAS DataBase Reference: oenothein B(CAS DataBase Reference)
• NIST Chemistry Reference: oenothein B(104987-36-2)
• EPA Substance Registry System: oenothein B(104987-36-2)

Safety Data

• WGK Germany: 3
• RTECS: LZ7000000
• Hazardous Substances Data: 104987-36-2(Hazardous Substances Data)

Usage

Description

Oenothein B is a macrocyclic ellagitannin, a type of polyphenolic compound, that can be derived from specific plant species such as Oenothera erythrosepala Bordas. It is known for its antitumor properties and its ability to inhibit certain enzymes, making it a potential candidate for pharmaceutical and therapeutic applications.

Uses

Used in Pharmaceutical Applications:
Oenothein B is used as an antitumor agent for its activity against MM2 ascites tumor. It demonstrates potential in the treatment of cancer due to its ability to inhibit tumor growth and progression.
Used in Enzyme Inhibition:
Oenothein B is used as an inhibitor for 5 alpha-reductase and aromatase enzymes. This application can be relevant in the treatment of conditions related to hormonal imbalances or enzyme overactivity, such as certain types of cancer or androgenetic disorders.

InChI:InChI=1/C68H50O44/c69-22-1-14(2-23(70)39(22)79)59(93)109-56-52(92)68(112-61(95)16-5-26(73)41(81)27(74)6-16)106-34-13-103-63(97)20-11-32(46(86)50(90)38(20)37-19(64(98)107-54(34)56)9-30(77)44(84)49(37)89)104-53-21(10-31(78)45(85)51(53)91)66(100)111-58-57(110-60(94)15-3-24(71)40(80)25(72)4-15)55-33(105-67(58)101)12-102-62(96)17-7-28(75)42(82)47(87)35(17)36-18(65(99)108-55)8-29(76)43(83)48(36)88/h1-11,33-34,52,54-58,67-92,101H,12-13H2/t33-,34-,52-,54+,55-,56+,57+,58-,67-,68+/m1/s1

Related news

Genotoxicity and cytotoxicity evaluation of oenothein B (cas 104987-36-2) and its protective effect against mitomycin C-induced mutagenic action07/17/2019

The natural product oenothein B (OeB), a dimeric macrocyclic ellagitannin, has a wide range of biological activities, such as antioxidant, anti-inflammatory, anti-viral, antifungal, and antitumor. However, investigations concerning its genotoxicity have not been carried out. This study assessed ...detailed

oenothein B (cas 104987-36-2) inhibits human non-small cell lung cancer A549 cell proliferation by ROS-mediated PI3K/Akt/NF-κB signaling pathway07/15/2019

Oenothein B has a wide range of biological activities. The present study probed into the underlying mechanism on how Oenothein B inhibits the proliferation of a lung cancer line A549. Our results showed that Oenothein B effectively inhibited the proliferation of A549 cells by inducing apoptosis ...detailed