1050424-03-7 Usage
Description
4-BORONO-2-(TRIFLUOROMETHYL)BENZOIC ACID is an organic compound characterized by the presence of a boron atom and a trifluoromethyl group attached to a benzoic acid structure. 4-BORONO-2-(TRIFLUOROMETHYL)BENZOIC ACID is known for its potential applications in the pharmaceutical and chemical industries due to its unique chemical properties and reactivity.
Uses
Used in Pharmaceutical Industry:
4-BORONO-2-(TRIFLUOROMETHYL)BENZOIC ACID is used as a reagent for the preparation of Novel 3H-[1,2,3]triazolo[4,5-c]pyridine derivatives. These derivatives are potential GPR119 agonists, which possess antidiabetic properties. The compound plays a crucial role in the synthesis of these potential therapeutic agents, contributing to the development of new treatments for diabetes.
Check Digit Verification of cas no
The CAS Registry Mumber 1050424-03-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,5,0,4,2 and 4 respectively; the second part has 2 digits, 0 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1050424-03:
(9*1)+(8*0)+(7*5)+(6*0)+(5*4)+(4*2)+(3*4)+(2*0)+(1*3)=87
87 % 10 = 7
So 1050424-03-7 is a valid CAS Registry Number.
1050424-03-7Relevant articles and documents
One-pot generation of lithium (lithiophenyl)trialkoxyborates from substituted dihalobenzenes (Hal = Br, I) and their derivatization with electrophiles
Kurach, Pawel,Lulinski, Sergiusz,Serwatowski, Janusz
experimental part, p. 3171 - 3178 (2009/05/30)
The simple one-pot approach to synthetically useful phenyltrialkoxyborates bearing lithium at the phenyl ring has been developed starting with 1,3- and 1,4-diiodobenzene, as well as several activated dibromobenzenes and bromoiodobenzenes. The general sequence of transformations involves halogen-lithium exchange by using nBuLi and subsequent boronation with a trialkylborate. The resulting lithium (halophenyl) trialkoxyborates were then subjected to halogen-lithium exchange in situ with a second equivalent of nBuLi to give dianionic lithium (lithiophenyl)trialkoxyborates. Treatment with selected electrophiles afforded substituted arylboronic acids and/or their pinacol esters as final products in moderate-to-good yields. Wiley-VCH Verlag GmbH & Co. KGaA, 2008.