1050501-88-6

Basic information

• Product Name: 2-Bromo-6-chloropyridin-3-amine
• Synonyms: 2-Bromo-6-chloropyridin-3-amine;3-Amino-2-bromo-6-chloropyridine;3-AMINO-6-CHLORO-2-BROMOPYRIDINE;2-Bromo-6-chloro-3-pyridinamine;2-Bromo-6-chloro-pyridin-3-ylamine
• CAS NO: 1050501-88-6
• Molecular Formula: C₅H₄BrClN₂
• Molecular Weight: 207.45566
• Mol File: 1050501-88-6.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 330.261 °C at 760 mmHg
• Flash Point: 153.537 °C
• Appearance: /
• Density: 1.834
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: -0.12±0.10(Predicted)
• CAS DataBase Reference: 2-Bromo-6-chloropyridin-3-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Bromo-6-chloropyridin-3-amine(1050501-88-6)
• EPA Substance Registry System: 2-Bromo-6-chloropyridin-3-amine(1050501-88-6)

Safety Data

• Hazardous Substances Data: 1050501-88-6(Hazardous Substances Data)

Usage

Description

2-Bromo-6-chloropyridin-3-amine is an organic compound characterized by the presence of a pyridine ring with a bromine atom at the 2nd position and a chlorine atom at the 6th position, along with an amine group attached to the 3rd position. 2-Bromo-6-chloropyridin-3-amine is known for its reactivity and is commonly utilized in the synthesis of various pharmaceutical compounds due to its unique structural features.

Uses

Used in Pharmaceutical Industry:
2-Bromo-6-chloropyridin-3-amine is used as a reactant for the synthesis of an Akt Kinase inhibitor, which is a significant compound in the development of pharmaceuticals targeting various diseases. Its role as a starting material is crucial in the production of numerous pharmaceutical compounds, highlighting its importance in the industry.
Additionally, 2-Bromo-6-chloropyridin-3-amine can be used as a building block in the synthesis of other bioactive molecules, further expanding its applications in the pharmaceutical sector. Its unique structural features make it a valuable component in the development of new drugs and therapeutic agents.

Upstream product

• 5350-93-6 6-Chloro-pyridin-3-ylamine 

Downstream Products

• 1352200-86-2 3-amino-6-chloro-pyridine-2-carboxylic acid ethyl ester 
• 800401-63-2 5-chloro-1H-pyrrolo[3 ,2-b]pyridine-2-carboxylic acid 
• 1199557-01-1 1-(difluoromethyl)-8-phenyl[1,2,4]triazolo[4,3-a][1,5]-naphthyridin-7(6H)-one 
• 1370618-02-2 1-(difluoromethyl)-8-phenyl[1,2,4]triazolo[4,3-a][1,5]-naphthyridin-7-yl trifluoromethanesulfonate 
• 1199557-02-2 7-chloro-1-(difluoromethyl)-8-phenyl-[1,2,4]triazolo[4,3-a]-1,5-naphthyridine 
• 1199557-04-4 tert-butyl (6-chloro-2-formylpyridin-3-yl)carbamate 
• 1227958-32-8 tert-butyl (2-bromo-6-chloropyridin-3-yl)carbamate 
• 65156-94-7 5-chloro-1H-pyrrolo[3,2-b]pyridine 
• 209286-85-1 5-chloro-1-(phenylsulfonyl)-1H-pyrrolo[3,2-b]pyridine 
• 31784-71-1 5-chlorothiazolo[5,4-b]pyridin-2-amine 

Relevant articles and documents

Substituent-Controlled Tailoring of Chalcogen-Bonded Supramolecular Nanoribbons in the Solid State

In this work, we design and synthesize supramolecular 2,5-substituted chalcogenazolo[5,4-β]pyridine (CGP) synthons arranging in supramolecular ribbons at the solid state. A careful choice of the combination of substituents at the 2- and 5-positions on the

NOVEL 1,3-DIHYDRO-2H-BENZIMIDAZOL-2-ONE DERIVATIVES SUBSTITUTED WITH HETEROCYCLES AS RESPIRATORY SYNCYTIAL VIRUS ANTIVIRAL AGENTS

The present invention is concerned with novel 1,3-dihydro-2H-benzimidazol-2-one derivatives substituted with heterocycles having formula (I) stereoisomeric forms thereof, and the pharmaceutically acceptable addition salts, and the solvates thereof, wherei

1,3 -DIHYDRO-2H-BENZIMIDAZOL-2-ONE DERIVATIVES SUBSTITUTED WITH HETEROCYCLES AS RESPIRATORY SYNCYTIAL VIRUS ANTIVIRAL AGENTS

The present invention is concerned with novel 4-substituted 1,3-dihydro-2H-benzimidazol-2-one derivatives substituted with heterocycles having formula (I) tautomers and stereoisomeric forms thereof, and the pharmaceutically acceptable addition salts, and the solvates thereof, wherein R4, R5, Z and Het have the meaning defined in the claims. The compounds according to the present invention are useful as inhibitors on the replication of the respiratory syncytial virus (RSV). The invention further concerns the preparation of such novel compounds, compositions comprising these compounds, and the compounds for use in the treatment of respiratory syncytial virus infection.